Department of Nuclear Medicine, Affiliated Hongqi Hospital of Mudanjiang Medical University, Mudanjiang, Heilongjiang 157011, China.
Department of Radiology, Affiliated Hongqi Hospital of Mudanjiang Medical University, Mudanjiang, Heilongjiang 157011, China.
J Infect Public Health. 2020 Sep;13(9):1347-1353. doi: 10.1016/j.jiph.2019.06.026. Epub 2019 Jul 6.
To compare the diagnostic efficacy and clinical application value of Positron Emission Tomography-Computed Tomography (PET-CT) metabolic computer Imaging imaging and Magnetic Resonance Imaging (MRI) diffusion imaging technology for regional lymph node metastasis in rectal cancer, 41 patients with rectal cancer confirmed by colonoscopy were collected and underwent 3.0T pelvic MRI and PET-CT examination, respectively. PET-CT/MRI fusion software was used to fuse magnetic resonance images and PET-CT images and accurately locate the rectal cancer lesions and lymph nodes, and image-operation-pathology control method was used to identify the lymph nodes around the rectum. In addition, independent sample t-test or Mann-Whitney U test were used to compare the differences in the values of various parameters between the two groups of metastatic lymph nodes and non-metastatic lymph nodes, Spearman correlation was used to analyze the correlation between SUV value and ADC value of metastatic lymph node, and the diagnostic value of SUV value and ADC value was evaluated by drawing ROC curve. The results showed that when SUV took 2.0 as the diagnostic threshold, the accuracy of PET-CT in diagnosing metastatic lymph nodes was 90.1%; when the diagnostic threshold of ADC was 1.0×10mm/s, the accuracy of DWI in diagnosing metastatic lymph nodes was 84.2%; the accuracy of the combination of the two methods for the diagnosis of metastatic lymph nodes was 94.4%. Therefore, it can be concluded that both PET-CT and MRI diffusion images were of high diagnostic value in the diagnosis of lymph node metastasis of rectal cancer, and their diagnostic results were highly consistent. When combined, the diagnostic accuracy can be further improved.
为了比较正电子发射断层扫描-计算机断层扫描（PET-CT）代谢计算机成像和磁共振成像（MRI）扩散成像技术在直肠癌区域淋巴结转移中的诊断效能和临床应用价值，收集了 41 例经结肠镜检查证实的直肠癌患者，分别进行 3.0T 盆腔 MRI 和 PET-CT 检查。使用 PET-CT/MRI 融合软件融合磁共振图像和 PET-CT 图像，准确定位直肠癌病灶和淋巴结，采用图像-手术-病理对照方法识别直肠周围淋巴结。此外，采用独立样本 t 检验或 Mann-Whitney U 检验比较两组转移性淋巴结和非转移性淋巴结各参数值的差异，采用 Spearman 相关分析 SUV 值与转移性淋巴结 ADC 值的相关性，通过绘制 ROC 曲线评价 SUV 值和 ADC 值的诊断价值。结果显示，当 SUV 取 2.0 作为诊断阈值时，PET-CT 诊断转移性淋巴结的准确率为 90.1%；当 ADC 的诊断阈值为 1.0×10mm/s 时，DWI 诊断转移性淋巴结的准确率为 84.2%；两种方法联合诊断转移性淋巴结的准确率为 94.4%。因此，可以得出结论，PET-CT 和 MRI 扩散图像在直肠癌淋巴结转移的诊断中均具有较高的诊断价值，其诊断结果高度一致。联合使用时，可以进一步提高诊断准确性。
