甲状腺乳头状癌所致胸腔积液。
Pleural fluid due to papillary thyroid cancer.
作者信息
Tamura Tomohiro, Shiozawa Toshihiro, Satoh Hiroaki, Kurishima Koichi, Kagohashi Katsunori, Takayashiki Norio, Hizawa Nobuyuki
机构信息
Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Ibaraki 310-0015, Japan.
Faculty of Medicine, Mito Medical Center, University of Tsukuba, Ibaraki 310-0015, Japan.
出版信息
Oncol Lett. 2019 Jul;18(1):962-966. doi: 10.3892/ol.2019.10383. Epub 2019 May 21.
We report herein a rare case of massive pleural effusion caused by papillary thyroid cancer, which was accompanied by multiple pulmonary metastasis. A 91-year-old male patient presented with shortness of breath due to massive right pleural fluid. Cytological specimens, which were obtained from pleural fluid by thoracentesis, and was consistent with that observed in surgically resected thyroid cancer 6-year previously. Immunocytochemical staining of the cells was positive for cytokeratin (CK)-7, CK-19, and positive for thyroglobulin. Massive pleural fluid due to a metastatic from papillary thyroid cancer is very rare but may develop in long-term survivors with this disease as observed in this case.
我们在此报告一例罕见的由乳头状甲状腺癌引起的大量胸腔积液病例，该病例伴有多处肺转移。一名91岁男性患者因右侧大量胸腔积液出现呼吸急促。通过胸腔穿刺术从胸腔积液中获取的细胞学标本，与6年前手术切除的甲状腺癌中观察到的标本一致。细胞的免疫细胞化学染色显示细胞角蛋白（CK）-7、CK-19呈阳性，甲状腺球蛋白呈阳性。乳头状甲状腺癌转移导致的大量胸腔积液非常罕见，但正如本例所示，在该疾病的长期存活者中可能会发生。
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