Berglund O, Beckman S, Grillner L, Jansson B, Lidbrink P, Karlsson A, Morfeldt-Månsson L, Pehrson P O, Törngren M, Wiechel B
Department of Environment, Health, and Infectious Diseases Controls, Karolinska Hospital, Stockholm, Sweden.
AIDS. 1988 Feb;2(1):51-4.
Thirty-five out of approximately 800 known HIV-seropositive people in Stockholm by mid-1986 were blood donors during the period 1979-1986. Almost all, i.e. 349 recipients of their blood components (red blood cells, platelets, plasma) could be traced. One hundred and eighty were still alive and 112 of these on further analysis, were suspected of being infected. They were contacted and all but one agreed to be tested for HIV antibodies. Fifty recipients were found to be seropositive. They had been transfused with blood components from 14 of the 35 donors. The earliest observed transmission occurred in June 1982. The patterns of HIV transmission showed, with only one exception, that each donor who had transmitted HIV to one recipient had also transmitted it to all later recipients. Appropriate preserved sera and clinical records from five of the donors who had not transmitted the virus were found and analysed. The result indicated that these donors had acquired their HIV infection after their last blood donation. In conclusion, our study indicates that every antibody-positive donor transmits HIV to almost every recipient.
到1986年年中，斯德哥尔摩约800名已知的HIV血清反应阳性者中有35人在1979年至1986年期间曾是献血者。几乎所有接受过他们血液成分（红细胞、血小板、血浆）的人（即349人）都能被追踪到。180人仍然存活，其中112人经进一步分析被怀疑受到感染。与他们取得了联系，除一人外，其他人都同意接受HIV抗体检测。发现50名接受者血清反应呈阳性。他们接受了来自35名献血者中14人的血液成分输血。最早观察到的传播发生在1982年6月。HIV传播模式显示，只有一个例外，即每一位将HIV传播给一名接受者的献血者也将其传播给了所有后来的接受者。找到了未传播病毒的5名献血者的适当保存血清和临床记录并进行了分析。结果表明，这些献血者是在他们最后一次献血后感染HIV的。总之，我们的研究表明，每一位抗体阳性献血者几乎会将HIV传播给每一位接受者。
