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Sigma-2 receptor as a potential therapeutic target for treating central nervous system disorders.

作者信息

Terada Kazuki, Migita Keisuke, Matsushima Yukari, Kamei Chiaki

机构信息

Laboratory of Drug Design and Drug Delivery, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.

Department of Drug Informatics, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.

出版信息

Neural Regen Res. 2019 Nov;14(11):1893-1894. doi: 10.4103/1673-5374.259609.

DOI:10.4103/1673-5374.259609
PMID:31290438
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6676876/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43f1/6676876/a1c7e5a483e4/NRR-14-1893-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43f1/6676876/a1c7e5a483e4/NRR-14-1893-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43f1/6676876/a1c7e5a483e4/NRR-14-1893-g001.jpg

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Alzheimers Dement (N Y). 2019 Jan 23;5:20-26. doi: 10.1016/j.trci.2018.11.001. eCollection 2019.
2
Cholinesterase inhibitor rivastigmine enhances nerve growth factor-induced neurite outgrowth in PC12 cells via sigma-1 and sigma-2 receptors.胆碱酯酶抑制剂利伐斯的明通过σ-1 和 σ-2 受体增强神经生长因子诱导的 PC12 细胞突起生长。
PLoS One. 2018 Dec 17;13(12):e0209250. doi: 10.1371/journal.pone.0209250. eCollection 2018.
3
Sigma-2 受体——从基础生物学到治疗靶点：关注与年龄相关的退行性疾病。
Int J Mol Sci. 2023 Mar 26;24(7):6251. doi: 10.3390/ijms24076251.
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Development of a CRISPRi Human Retinal Pigmented Epithelium Model for Functional Study of Age-Related Macular Degeneration Genes.用于年龄相关性黄斑变性基因功能研究的CRISPRi人类视网膜色素上皮细胞模型的构建
Int J Mol Sci. 2023 Feb 8;24(4):3417. doi: 10.3390/ijms24043417.
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Overview of Sigma-1R Subcellular Specific Biological Functions and Role in Neuroprotection.Sigma-1R 亚细胞特定生物学功能概述及其在神经保护中的作用。
Int J Mol Sci. 2023 Jan 19;24(3):1971. doi: 10.3390/ijms24031971.
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Sigma receptors and neurological disorders.Sigma 受体与神经疾病。
Pharmacol Rep. 2021 Dec;73(6):1582-1594. doi: 10.1007/s43440-021-00310-7. Epub 2021 Aug 5.
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Int J Biochem Cell Biol. 2020 Sep;126:105803. doi: 10.1016/j.biocel.2020.105803. Epub 2020 Jul 12.
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