Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia.
Tropical Infectious Diseases Research and Education Centre (TIDREC), University of Malaya, Kuala Lumpur, Malaysia.
J Med Entomol. 2019 Oct 28;56(6):1715-1725. doi: 10.1093/jme/tjz117.
Resistance status of Aedes albopictus (Diptera: Culicidae) collected from Sabah, East Malaysia, was evaluated against four major classes of adulticides, namely pyrethroid, carbamate, organochlorine, and organophosphate. Adult bioassays conforming to WHO standard protocols were conducted to assess knockdown and mortality rates of Ae. albopictus. Among tested pyrethroid adulticides, only cyfluthrin, lambda-cyaholthrin, and deltamethrin were able to inflict total knockdown. The other adulticide classes mostly failed to cause any knockdown; the highest knockdown rate was only 18.33% for propoxur. With regards to mortality rate, Ae. albopictus was unanimously susceptible toward all pyrethroids, dieldrin, and malathion, but exhibited resistance toward bendiocarb, propoxur, dichlorodiphenyltrichloroethane, and fenitrothion. Additionally, correlation analysis demonstrated cross-resistance between bendiocarb and propoxur, and malathion and propoxur. In conclusion, this study has disclosed that pyrethroids are still generally effective for Aedes control in Sabah, Malaysia. The susceptibility status of Ae. albopictus against pyrethroids in descending order was cyfluthrin > lambda-cyhalothrin > deltamethrin > etofenprox > permethrin.
从马来西亚沙巴州采集的白纹伊蚊（双翅目：蚊科）对四种主要类别的杀虫剂（拟除虫菊酯、氨基甲酸酯、有机氯和有机磷）的抗药性进行了评估。按照世界卫生组织标准方案进行了成蚊生物测定，以评估白纹伊蚊的击倒和死亡率。在所测试的拟除虫菊酯类杀虫剂中，只有氯氟氰菊酯、氯氰菊酯和溴氰菊酯能够造成完全击倒。其他杀虫剂类别的杀虫剂大多未能造成任何击倒；最高击倒率仅为 18.33%的是残杀威。关于死亡率，白纹伊蚊对所有拟除虫菊酯、狄氏剂和马拉硫磷均敏感，但对苯氧威、残杀威、滴滴涕和三氯杀螨醇表现出抗药性。此外，相关分析表明，苯氧威和残杀威之间以及马拉硫磷和残杀威之间存在交叉抗性。总之，本研究表明拟除虫菊酯类杀虫剂在马来西亚沙巴州仍然是有效的蚊虫控制方法。白纹伊蚊对拟除虫菊酯类杀虫剂的敏感性依次为氯氟氰菊酯>氯氰菊酯>溴氰菊酯>乙氰菊酯>氯菊酯。
