Catinean Adrian, Neag Maria Adriana, Tulbure Mihaela
Department of Internal Medicine, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Department of Pharmacology, Toxicology and Clinical Pharmacology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Turk J Gastroenterol. 2019 Jul;30(7):636-640. doi: 10.5152/tjg.2019.18784.
BACKGROUND/AIMS: The purpose of this prospective study was to compare patients' discomfort during water immersion (WI) colonoscopy without sedation or available on request, with that of patients during air insufflation (AI) colonoscopy with sedation, in the ambulatory setting.
A prospective observational study was conducted in 100 patients who performed a colonoscopy between August 2015 and February 2016 in an Ambulatory Gastroenterology Center in Cluj-Napoca, Romania. They were divided into two branches A and B. Patients in Group A underwent a classic colonoscopy with AI and standard sedation (2 mg of midazolam and 50 mg of tramadol), while patients in Group B underwent an unsedated or on demand sedation colonoscopy with WI technique.
The patients in group A presented a higher discomfort (statistically significant) compared to those in group B, and had also the median total discomfort score higher than those in group B. The patients in group A had also a higher discomfort score after examination. The total time of examination was the same in the two groups, but in group B the progression to cecum time was 3 minutes lower than for those in group A. A greater discomfort of the patient was correlated with the longer time required to reach the cecum.
In conclusion, WI colonoscopy is superior to AI technique in reducing insertion pain, progression-to-cecum time, minimizing sedation requirements and also in the willingness to repeat the technique.
背景/目的:这项前瞻性研究的目的是比较在门诊环境中,非镇静或按需镇静的水浸式(WI)结肠镜检查患者与镇静状态下空气注入式(AI)结肠镜检查患者的不适程度。
对2015年8月至2016年2月间在罗马尼亚克卢日-纳波卡的一家门诊胃肠病中心接受结肠镜检查的100例患者进行了一项前瞻性观察研究。他们被分为A、B两组。A组患者接受经典的AI结肠镜检查和标准镇静(2毫克咪达唑仑和50毫克曲马多),而B组患者接受非镇静或按需镇静的WI技术结肠镜检查。
与B组患者相比,A组患者的不适感更高(具有统计学意义),且总不适评分中位数也高于B组。A组患者检查后的不适评分也更高。两组的总检查时间相同,但B组到达盲肠的时间比A组短3分钟。患者不适感更强与到达盲肠所需时间更长相关。
总之,WI结肠镜检查在减轻插入疼痛、缩短到达盲肠时间、减少镇静需求以及患者重复该技术的意愿方面优于AI技术。