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神经根病罕见病例:骶骨单发性骨纤维异常增殖症

A Rare Case of Radiculopathy: Monostotic Fibrous Dysplasia of the Sacrum.

作者信息

Teixeira Joaquim Cruz, Simão Diogo Cardoso, Pimentel José, Livraghi Sérgio

机构信息

Department of Neurosurgery. Hospital de Santa Maria. Centro Hospitalar de Lisboa Norte. Lisbon. Portugal.

Laboratory of Neuropathology. Department of Neurology. Hospital de Santa Maria. Centro Hospitalar de Lisboa Norte. Lisbon. Portugal.

出版信息

Acta Med Port. 2019 Jun 28;32(6):466-468. doi: 10.20344/amp.9331.

Abstract

Fibrous dysplasia is a bone disease characterized by an osteoblastic dysfunction resulting in a fibrous replacement of the normal medullary bone. We describe the case of a 33-year-old who presented with low back pain irradiating to her right leg. Both the computed tomography scan and magnetic resonance imaging showed an osteolytic, multicystic lesion of the right hemi-sacrum with invasion of the right S1 foramen. She underwent foraminotomy and curettage of the lesion. Histological diagnosis was fibrous dysplasia, without features of malignant transformation. Three years after surgery the patient is asymptomatic and imaging is stable. This is the fifth known case of monostotic fibrous dysplasia involving the sacrum, a rare entity that must be considered in the differential diagnosis when approaching patients with sacral lesions.

摘要

骨纤维异常增殖症是一种以成骨细胞功能障碍为特征的骨病,可导致正常髓质骨被纤维组织替代。我们报告一例33岁女性,她因下背部疼痛放射至右腿前来就诊。计算机断层扫描和磁共振成像均显示右半骶骨有溶骨性、多囊性病变,并侵犯右侧S1椎间孔。她接受了椎间孔切开术和病变刮除术。组织学诊断为骨纤维异常增殖症,无恶变特征。术后三年,患者无症状,影像学表现稳定。这是已知第五例单发性骨纤维异常增殖症累及骶骨的病例,骶骨病变患者进行鉴别诊断时必须考虑到这种罕见情况。

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