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微创固定与处理即将发生病理性骨折的骶骨纤维发育不良:病例展示

Minimally invasive fixation and management of sacral fibrous dysplasia with impending pathological fracture: illustrative case.

作者信息

Kress Dustin J, Garcia Rafael, Haselhuhn Jason J, Zhou Yan, Murugan Paari, Sembrano Jonathan N

机构信息

Department of Orthopedic Surgery, University of Minnesota, Minneapolis, Minnesota.

Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.

出版信息

J Neurosurg Case Lessons. 2025 Jun 30;9(26). doi: 10.3171/CASE25159.

Abstract

BACKGROUND

Fibrous dysplasia (FD) is a rare, benign fibro-osseous disorder that can compromise structural integrity, particularly in weight-bearing bones like the sacrum. Managing sacral FD is challenging due to the need for both lesion control and biomechanical stabilization.

OBSERVATIONS

A 34-year-old woman presented with chronic right sacral pain, functional impairment, and a large lytic lesion in the right sacral ala, later confirmed as FD. Conservative treatment, including physical therapy and epidural steroid injection, failed to provide relief. Imaging revealed an impending pathological fracture, prompting surgical intervention. A minimally invasive approach, including curettage, bone grafting, and iliosacral fixation with ingrowth screws, was performed. The patient experienced significant pain relief, functional improvement, and sustained stability, with 2-year follow-up confirming stable fixation and complete lesion filling.

LESSONS

This case highlights the role of minimally invasive sacropelvic fixation in preventing structural failure in sacral FD. Integrating biomechanical stabilization with targeted lesion management optimizes outcomes. Long-term follow-up is essential to monitor implant stability and bone remodeling. https://thejns.org/doi/10.3171/CASE25159.

摘要

背景

骨纤维异常增殖症(FD)是一种罕见的良性纤维-骨疾病,可损害结构完整性,尤其是在像骶骨这样的负重骨中。由于需要同时控制病变和进行生物力学稳定,骶骨FD的治疗具有挑战性。

观察结果

一名34岁女性出现慢性右骶骨疼痛、功能障碍,右侧骶骨翼有一个大的溶骨性病变,后来确诊为FD。包括物理治疗和硬膜外类固醇注射在内的保守治疗未能缓解症状。影像学检查显示即将发生病理性骨折,促使进行手术干预。采用了一种微创方法,包括刮除、骨移植和使用长入式螺钉进行髂骶固定。患者疼痛明显缓解,功能改善,且保持稳定,2年的随访证实固定稳定且病变完全填充。

经验教训

本病例突出了微创骶骨盆固定在预防骶骨FD结构破坏中的作用。将生物力学稳定与针对性的病变管理相结合可优化治疗效果。长期随访对于监测植入物稳定性和骨重塑至关重要。https://thejns.org/doi/10.3171/CASE25159

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e4/12210070/c01b4dbfe798/CASE25159_figure_1.jpg

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