An iPSC Model Reveals Mechanisms of Interindividual Differences in Pain.
作者信息
Naka Alexander
机构信息
Department of Neuroscience, Genentech, South San Francisco, California 94080
出版信息
J Neurosci. 2019 Jul 10;39(28):5422-5423. doi: 10.1523/JNEUROSCI.0602-19.2019.
Abstract
摘要
相似文献
1
An iPSC Model Reveals Mechanisms of Interindividual Differences in Pain.一种诱导多能干细胞模型揭示了个体间疼痛差异的机制。
J Neurosci. 2019 Jul 10;39(28):5422-5423. doi: 10.1523/JNEUROSCI.0602-19.2019.
2
Transcriptome Profiling Reveals Degree of Variability in Induced Pluripotent Stem Cell Lines: Impact for Human Disease Modeling.转录组分析揭示诱导多能干细胞系的变异程度：对人类疾病建模的影响。
Cell Reprogram. 2015 Oct;17(5):327-37. doi: 10.1089/cell.2015.0009. Epub 2015 Sep 8.
3
Do Induced Pluripotent Stem Cell Characteristics Correlate with Efficient In Vitro Smooth Muscle Cell Differentiation? A Comparison of Three Patient-Derived Induced Pluripotent Stem Cell Lines.诱导多能干细胞特性是否与体外平滑肌细胞高效分化相关？三种患者来源的诱导多能干细胞系的比较。
Stem Cells Dev. 2018 Oct 15;27(20):1438-1448. doi: 10.1089/scd.2018.0031. Epub 2018 Aug 28.
4
Induced Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium: A Comparative Study Between Cell Lines and Differentiation Methods.诱导多能干细胞来源的视网膜色素上皮细胞：细胞系与分化方法的比较研究
J Ocul Pharmacol Ther. 2016 Jun;32(5):317-30. doi: 10.1089/jop.2016.0022. Epub 2016 May 16.
5
Structural Changes in N-Glycans on Induced Pluripotent Stem Cells Differentiating Toward Cardiomyocytes.诱导多能干细胞向心肌细胞分化过程中N-聚糖的结构变化
Stem Cells Transl Med. 2015 Nov;4(11):1258-64. doi: 10.5966/sctm.2015-0029. Epub 2015 Sep 16.
6
Metformin induces osteoblastic differentiation of human induced pluripotent stem cell-derived mesenchymal stem cells.二甲双胍诱导人诱导多能干细胞来源的间充质干细胞成骨分化。
J Tissue Eng Regen Med. 2018 Feb;12(2):437-446. doi: 10.1002/term.2470. Epub 2017 Aug 11.
7
Matrix-assisted laser desorption/ionization imaging mass spectrometry reveals changes of phospholipid distribution in induced pluripotent stem cell colony differentiation.基质辅助激光解吸/电离成像质谱法揭示了诱导多能干细胞集落分化过程中磷脂分布的变化。
Anal Bioanal Chem. 2017 Feb;409(4):1007-1016. doi: 10.1007/s00216-016-0015-x. Epub 2016 Nov 4.
8
Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins.在确定的条件下使用纯化的细胞外基质蛋白将人多能干细胞分化为视网膜色素上皮细胞。
J Tissue Eng Regen Med. 2013 Aug;7(8):642-53. doi: 10.1002/term.1458. Epub 2012 Apr 18.
9
Illustrating the potency of current Good Manufacturing Practice-compliant induced pluripotent stem cell lines as a source of multiple cell lineages using standardized protocols.利用标准化方案阐明符合现行良好生产规范的诱导多能干细胞系作为多种细胞谱系来源的效力。
Cytotherapy. 2018 Jun;20(6):861-872. doi: 10.1016/j.jcyt.2018.03.037. Epub 2018 May 21.
10
An in Vitro and in Vivo Study of the Effect of Dexamethasone on Immunoinhibitory Function of Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells.地塞米松对诱导多能干细胞衍生间充质干细胞免疫抑制功能的体外和体内研究。
Cell Transplant. 2018 Sep;27(9):1340-1351. doi: 10.1177/0963689718780194. Epub 2018 Jul 30.
引用本文的文献
1
Development of a functional human induced pluripotent stem cell-derived nociceptor MEA system as a pain model for analgesic drug testing.开发一种功能性人诱导多能干细胞衍生的伤害感受器微电极阵列系统作为镇痛药测试的疼痛模型。
Front Cell Dev Biol. 2023 Mar 1;11:1011145. doi: 10.3389/fcell.2023.1011145. eCollection 2023.
本文引用的文献
1
Defining the Functional Role of Na1.7 in Human Nociception.定义 Na1.7 在人类痛觉中的功能作用。
Neuron. 2019 Mar 6;101(5):905-919.e8. doi: 10.1016/j.neuron.2019.01.047. Epub 2019 Feb 19.
2
Resilience to Pain: A Peripheral Component Identified Using Induced Pluripotent Stem Cells and Dynamic Clamp.疼痛耐受力：使用诱导多能干细胞和动态钳位技术鉴定的外周组成部分。
J Neurosci. 2019 Jan 16;39(3):382-392. doi: 10.1523/JNEUROSCI.2433-18.2018. Epub 2018 Nov 20.
3
Neural stem cells and epilepsy: functional roles and disease-in-a-dish models.神经干细胞与癫痫：功能作用和疾病在玻璃器皿中的模型。
Cell Tissue Res. 2018 Jan;371(1):47-54. doi: 10.1007/s00441-017-2675-z. Epub 2017 Aug 22.
4
A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients.一种有害的Nav1.1突变选择性地损害了源自德雷维特综合征患者的端脑抑制性神经元。
Elife. 2016 Jul 26;5:e13073. doi: 10.7554/eLife.13073.
5
Genetic predictors of human chronic pain conditions.人类慢性疼痛状况的遗传预测指标。
Neuroscience. 2016 Dec 3;338:36-62. doi: 10.1016/j.neuroscience.2016.04.041. Epub 2016 Apr 30.
6
Pharmacotherapy for Pain in a Family With Inherited Erythromelalgia Guided by Genomic Analysis and Functional Profiling.基于基因组分析和功能谱分析指导的遗传性红细胞增多症家族性疼痛的药物治疗。
JAMA Neurol. 2016 Jun 1;73(6):659-67. doi: 10.1001/jamaneurol.2016.0389.
7
Inherited erythromelalgia due to mutations in SCN9A: natural history, clinical phenotype and somatosensory profile.遗传性红细胞增多性红斑肢痛症：SCN9A 突变所致：自然病史、临床表型和躯体感觉特征。
Brain. 2016 Apr;139(Pt 4):1052-65. doi: 10.1093/brain/aww007. Epub 2016 Feb 26.
8
The Na(V)1.7 sodium channel: from molecule to man.钠离子通道 Na(V)1.7：从分子到人。
Nat Rev Neurosci. 2013 Jan;14(1):49-62. doi: 10.1038/nrn3404. Epub 2012 Dec 12.
9
Twin studies of pain.疼痛的双胞胎研究。
Clin Genet. 2012 Oct;82(4):331-40. doi: 10.1111/j.1399-0004.2012.01938.x. Epub 2012 Aug 13.
10
Heritability of chronic pain in 2195 extended families.2195 个扩展家族的慢性疼痛遗传性。
Eur J Pain. 2012 Aug;16(7):1053-63. doi: 10.1002/j.1532-2149.2011.00095.x. Epub 2012 Jan 26.
Zotero 插件