Department of Microbiology and Immunology, University at Buffalo School of Medicine, Buffalo, New York, USA
mSphere. 2019 Jul 10;4(4):e00326-19. doi: 10.1128/mSphere.00326-19.
Elsa N. Bou Ghanem works in the field of innate immune senescence, inflammation, and host defense. In this mSphere of Influence article, she reflects on how "Adenosine A receptor deficiency promotes host defenses against Gram-negative bacterial pneumonia" by Barletta et al. (K. E. Barletta, R. E. Cagnina, M. D. Burdick, J. Linden, and B. Mehrad, Am J Respir Crit Care Med 186:1044-1050, 2012, https://doi.org/10.1164/rccm.201204-0622OC) impacted her own work examining the role of the extracellular adenosine pathway in neutrophil responses and host defense against pneumococcal pneumonia.
埃尔莎·N·布甘尼在先天免疫衰老、炎症和宿主防御领域工作。在本期《mSphere》影响力文章中,她反思了巴雷塔等人的研究成果“Adenosine A receptor deficiency promotes host defenses against Gram-negative bacterial pneumonia”(《腺苷 A 受体缺失促进宿主防御革兰氏阴性菌性肺炎》)(K. E. Barletta, R. E. Cagnina, M. D. Burdick, J. Linden, and B. Mehrad, Am J Respir Crit Care Med 186:1044-1050, 2012, https://doi.org/10.1164/rccm.201204-0622OC)如何影响她自己的工作,即研究细胞外腺苷途径在中性粒细胞反应和宿主防御肺炎链球菌性肺炎中的作用。