Yasuda Shusuke, Sowa Yoshihiro, Hashimoto Hiroyuki, Nakagami Takuya, Tsuno Takuo, Sakai Toshiyuki
Department of Molecular-Targeting Cancer Prevention, Kyoto Prefectural University of Medicine.
Tsuno Food Industrial Co., Ltd.
J Oleo Sci. 2019 Aug 1;68(8):765-768. doi: 10.5650/jos.ess19054. Epub 2019 Jul 10.
γ-Oryzanol is a naturally occurring component of rice bran and consists of various steryl ferulates. The antioxidant activities of γ-oryzanol have mostly been demonstrated in cell-free systems. Therefore, we determined whether steryl ferulate of γ-oryzanol suppress spontaneous intracellular reactive oxygen species (ROS) in cell-based systems. We found that cycloartenyl ferulate and β-sitosteryl ferulate suppressed spontaneous intracellular ROS in a similar way to N-acetylcysteine and α-tocopherol.
γ-谷维素是米糠中的一种天然成分，由多种阿魏酸甾醇组成。γ-谷维素的抗氧化活性大多已在无细胞体系中得到证实。因此，我们测定了γ-谷维素中的阿魏酸甾醇是否能在细胞体系中抑制细胞内自发产生的活性氧（ROS）。我们发现，阿魏酸环阿屯酯和阿魏酸β-谷甾醇抑制细胞内自发产生的ROS的方式与N-乙酰半胱氨酸和α-生育酚相似。
