Ubukawa Kumi, Kameoka Yoshihiro, Guo Yong-Mei, Nara Miho, Watanabe Atsushi, Fujishima Masumi, Fujishima Naohito, Yoshioka Tomoko, Takahashi Naoto
Department of Hematology, Nephrology and Rheumatology, Akita University, Japan.
Intern Med. 2019 Nov 1;58(21):3153-3156. doi: 10.2169/internalmedicine.2967-19. Epub 2019 Jul 10.
A 53-year-old woman presented at our hospital due to nasal bleeding and petechiae with profound thrombocytopenia (0.4×10/L). Her platelet count returned to the normal range immediately following a platelet transfusion. In this case, tea brewed from Taxus yunnanensis was the only suspected agent ingested prior to the onset of thrombocytopenia while all other etiologies for thrombocytopenia were excluded. A re-exposure test to Taxus yunnanensis resulted in the recurrence of acute thrombocytopenia. The association of thrombocytopenia with substances other than drugs has so far only been rarely described and to the best of our knowledge, this is the first reported case of thrombocytopenia caused by Taxus yunnanensis.
一名53岁女性因鼻出血和瘀点伴严重血小板减少（0.4×10⁹/L）就诊于我院。输注血小板后其血小板计数立即恢复至正常范围。在该病例中，云南红豆杉泡的茶是血小板减少发作前唯一摄入的可疑物质，而血小板减少的所有其他病因均被排除。对云南红豆杉的再次接触试验导致急性血小板减少复发。血小板减少与药物以外物质的关联迄今仅有很少的描述，据我们所知，这是首例由云南红豆杉引起血小板减少的报道病例。
