Diaz Edward C, Velasquez Monica G, Kao Chia-Sui, Wu Hsi-Yang
Department of Urology, Stanford University Medical Center, 300 Pasteur Drive, RM-S-287, Grant Building, 2nd Floor, Stanford, CA, 94305, USA.
Department of Pathology, Stanford University Medical Center, 300 Pasteur Drive, RMH1402, MC 5626, Stanford, CA, 94305, USA.
Urol Case Rep. 2019 Jun 20;26:100948. doi: 10.1016/j.eucr.2019.100948. eCollection 2019 Sep.
Bladder cancer is rare in the pediatric population, and clear cell carcinoma is extremely rare with one other pediatric case reported. Here we report the clinical outcome for a medically complicated pediatric patient with muscle invasive clear cell carcinoma treated with partial cystectomy without neoadjuvant or adjuvant therapy. Final pathology was stage T2bN0M0 with negative margins. At 2 years, there is no disease recurrence by cystoscopy, chest and abdominal imaging. Postoperative issues have been related to reduced bladder capacity and compliance and the patient is currently managed with continuous urinary diversion and will require future definitive lower tract reconstruction.
膀胱癌在儿科人群中较为罕见，透明细胞癌极其罕见，此前仅报道过一例儿科病例。在此，我们报告一名患有肌肉浸润性透明细胞癌的儿科复杂病例的临床结果，该患者接受了部分膀胱切除术，未进行新辅助或辅助治疗。最终病理分期为T2bN0M0，切缘阴性。术后2年，膀胱镜检查、胸部和腹部影像学检查均未发现疾病复发。术后问题与膀胱容量减少和顺应性有关，患者目前通过持续尿液改道进行管理，未来需要进行确定性的下尿路重建。
