a Department of Family & Community Health, University of Pennsylvania School of Nursing , Philadelphia , PA , USA.
b Department of Communication Studies, Indiana University-Purdue University Indianapolis , Indianapolis , IN , USA.
Hum Vaccin Immunother. 2019;15(7-8):1824-1830. doi: 10.1080/21645515.2019.1625642. Epub 2019 Jul 11.
The human papillomavirus (HPV) vaccine has been available in the United States for over a decade. We sought to examine the associations between self-reported receipt of HPV vaccination among women and their 11-14-year-old children in 27 low-coverage states. Among the 3,261 mothers we surveyed, 18% reported receiving ≥1 dose of HPV vaccine. A significantly higher proportion of vaccinated women reported vaccination of their children compared to unvaccinated women (83% vs. 56%, < .001). In multivariable logistic regression, vaccinated women (vs. unvaccinated) had 3.58 (95% CI: 2.81-4.56) times the adjusted-odds of vaccinating their children (≥1 dose HPV vaccine). Among unvaccinated children, vaccinated mothers (vs. unvaccinated) had 3.32 (95% CI: 2.09-5.26) times the adjusted odds of high intention to vaccinate their children in the next 12 months. We did not observe associations between mothers' vaccination confidence and their vaccination status. We conclude that mothers who received ≥1 dose of HPV vaccine may be more likely to initiate or highly intend to initiate the HPV vaccine series for their children. This may have important implications for meeting population goals for HPV vaccination coverage as an increasing proportion of mothers are likely to be vaccinated over time.
人类乳头瘤病毒（HPV）疫苗在美国已经使用了十多年。我们试图研究在 27 个低覆盖率州中，报告接受 HPV 疫苗接种的女性及其 11-14 岁子女之间的关联。在我们调查的 3261 位母亲中，18%报告接受了≥1 剂 HPV 疫苗。与未接种疫苗的女性相比，接种疫苗的女性报告其子女接种疫苗的比例显著更高（83%对 56%，<.001）。在多变量逻辑回归中，与未接种疫苗的女性相比，接种疫苗的女性（与未接种疫苗的女性相比）有 3.58 倍（95%CI：2.81-4.56）调整后的子女接种疫苗（≥1 剂 HPV 疫苗）的可能性。在未接种疫苗的儿童中，与未接种疫苗的母亲相比，接种疫苗的母亲（与未接种疫苗的母亲相比）有 3.32 倍（95%CI：2.09-5.26）调整后的子女在未来 12 个月内高度打算接种疫苗的可能性。我们没有观察到母亲接种疫苗的信心与其接种疫苗的状况之间存在关联。我们得出结论，接受≥1 剂 HPV 疫苗的母亲可能更有可能为其子女启动或高度打算启动 HPV 疫苗系列。随着越来越多的母亲随着时间的推移接种疫苗，这可能对实现 HPV 疫苗接种覆盖率的人群目标产生重要影响。
