Department of Medicine, Division of Infectious Diseases, Hamad Medical Corporation, Doha, Qatar.
Histopathology Department, Hamad Medical Corporation, Doha, Qatar.
Int J Infect Dis. 2019 Sep;86:167-170. doi: 10.1016/j.ijid.2019.07.002. Epub 2019 Jul 8.
Schistosomiasis is the third most widespread devastating parasitic disease worldwide and has a high mortality burden. Neuroschistosomiasis is one of the rare and most severe clinical presentations of the disease. It is caused by granuloma formation around eggs that lodge in the central nervous system, with Schistosoma japonicum usually causing most reported cerebral disease. Three unusual presentations of schistosomiasis in Qatar are described herein. The three patients were young males who presented with seizures and tumor-like lesions on brain imaging. The diagnosis was confirmed by biopsy, which showed necrotizing granulomas containing Schistosoma eggs. These cases raise awareness of neuroschistosomiasis as a potential cause of tumor-like brain lesions in migrants and returning travelers from endemic areas.
血吸虫病是全球第三大流行的破坏性寄生虫病，具有较高的死亡率负担。神经血吸虫病是该病罕见且最严重的临床表现之一。它是由在中枢神经系统中滞留的虫卵周围的肉芽肿形成引起的，日本血吸虫通常导致大多数报道的脑部疾病。本文描述了卡塔尔的三种不常见的血吸虫病表现。这 3 名患者均为年轻男性，表现为癫痫发作和脑部影像学上的肿瘤样病变。诊断通过活检得到确认，活检显示含有血吸虫卵的坏死性肉芽肿。这些病例提醒人们注意神经血吸虫病，因为它是来自流行地区的移民和返回旅行者的肿瘤样脑部病变的潜在原因。
