a Department of Nephrology , Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital , Chengdu , China.
b Department of Nephrology , Sichuan Provincial Ziyang People's Hospital , Ziyang , China.
Ren Fail. 2019 Nov;41(1):644-649. doi: 10.1080/0886022X.2019.1612429.
To investigate the incidence, pathogenesis, as well as mortality rate and causes of end-stage renal disease patients with hemodialysis (ESRD-HD) in Sichuan province of China. In this retrospective descriptive study, all the data were exported from the Chinese National Renal Data System (CNRDS). The demographic and pathogenic information from 01 January 2011 to 31 December 2016 were statistically analyzed. According to the data from CNRDS, the incidence of ESRD-HD was high in Sichuan province. From 2011 to 2016, the annual incidence rate of ESRD-HD was 61.84, 73.75, 78.04, 66.04, 72.61, and 60.98 per million population (pmp). Male ESRD-HD patients were higher than female patients (1.5:1). The major causes of ESRD-HD in Sichuan province from 2011 to 2016 were chronic glomerulonephritis and diabetic nephropathy. The annual mortality rate of ESRD-HD was 113.20, 91.25, 73.02, 68.56, 68.57, and 58.39 per 1000 person-years. The descending rate of mortality was parallel in both males and females. The mortality rate was observed to be higher in the elderly group (age ≥ 60). The major cause of mortality was cardiovascular diseases (24.48%). In Sichuan province, the incidence of ESRD-HD annually was gradually descending. The elderly and male patients had higher incidence of ESRD-HD. The annual mortality rate of ESRD-HD was declining year by year, and elderly patients aged ≥ 60 contributed to the highest mortality rates. The major cause of death was cardiovascular diseases. This could contribute to a better understanding of ESRD-HD in southwest of China, thus providing better treatment for ESRD in the future.
调查中国四川省血液透析（ESRD-HD）终末期肾病患者的发病率、发病机制、死亡率和死亡原因。在这项回顾性描述性研究中，所有数据均从中国国家肾脏数据系统（CNRDS）导出。对 2011 年 1 月 1 日至 2016 年 12 月 31 日的人口统计学和发病信息进行了统计分析。根据 CNRDS 的数据，四川省 ESRD-HD 的发病率较高。2011 年至 2016 年，ESRD-HD 的年发病率分别为 61.84、73.75、78.04、66.04、72.61 和 60.98/100 万人口（pmp）。男性 ESRD-HD 患者高于女性患者（1.5:1）。2011 年至 2016 年，四川省 ESRD-HD 的主要病因是慢性肾小球肾炎和糖尿病肾病。2011 年至 2016 年，ESRD-HD 的年死亡率分别为 113.20、91.25、73.02、68.56、68.57 和 58.39/1000 人年。男性和女性的死亡率呈下降趋势。老年组（年龄≥60 岁）死亡率较高。死亡的主要原因是心血管疾病（24.48%）。在四川省，ESRD-HD 的发病率呈逐年下降趋势。老年和男性患者 ESRD-HD 的发病率较高。ESRD-HD 的年死亡率逐年下降，年龄≥60 岁的老年患者死亡率最高。死亡的主要原因是心血管疾病。这有助于更好地了解中国西南部的 ESRD-HD，从而为未来的 ESRD 提供更好的治疗。
