From the Department of Radiology (A.E., M.W., W.W., R.H., M.K., M.S., M.B., M.U., M.M.M.), University Hospital Erlangen, Erlangen, Germany.
Imaging Science Institute (M.U., M.M.M.), Erlangen, Germany.
AJNR Am J Neuroradiol. 2019 Aug;40(8):1374-1382. doi: 10.3174/ajnr.A6108. Epub 2019 Jul 11.
CTA is the imaging modality of choice in many institutions for the evaluation of the supraaortic vessels, but radiation exposure remains a matter of concern. Our aim was to evaluate a 70-kV protocol for CT angiography of the carotid arteries with respect to image quality and radiation exposure compared with automated tube voltage adaption.
A total of 90 consecutive patients were included in this prospective study and randomized to the study group ( = 45, 70 kV) or control group ( = 45, automated tube voltage adaptation). Volume CT dose indices and dose-length products were recorded in the examination protocol. Image quality was assessed as arterial vessel contrast, signal-to-noise ratio, contrast-to-noise ratio, and contrast-to-noise ratio in reference to the radiation dose. Subjective overall image-quality analysis, image-artifact analysis, and diagnostic evaluation were performed by 2 observers by using a 4-point Likert scale.
Radiation exposure was significantly lower in the study group (volume CT dose index reduced by 22%, dose-length product reduction by 20%; each < .001). Contrast ( = .15), SNR ( = .4), and contrast-to-noise ratio ( = .5) did not show significant differences between the groups. The contrast-to-noise ratio in reference to the radiation dose was not significantly increased using the study protocol ( = .2). Subjective image quality and visualization of pathologic findings did not differ significantly between the groups.
Carotid CTA using the lowest available voltage (70 kV) is feasible at very-low-dose levels, while overall image quality is comparable with protocols using automated tube voltage selection.
CTA 是许多机构评估主动脉上血管的首选成像方式,但辐射暴露仍然是一个令人关注的问题。我们的目的是评估颈动脉 CT 血管造影的 70kV 方案在图像质量和辐射暴露方面与自动管电压自适应的比较。
本前瞻性研究共纳入 90 例连续患者,并随机分为研究组(n=45,70kV)和对照组(n=45,自动管电压自适应)。在检查方案中记录体积 CT 剂量指数和剂量长度产品。通过评估动脉血管对比度、信噪比、对比噪声比和参考辐射剂量的对比噪声比来评估图像质量。由 2 名观察者使用 4 分 Likert 量表进行主观整体图像质量分析、图像伪影分析和诊断评估。
研究组的辐射暴露明显降低(体积 CT 剂量指数降低 22%,剂量长度产品降低 20%;均<0.001)。两组之间的对比度( =.15)、信噪比( =.4)和对比噪声比( =.5)没有显著差异。使用研究方案,参考辐射剂量的对比噪声比没有显著增加( =.2)。主观图像质量和病理表现的可视化在两组之间没有显著差异。
使用最低可用电压(70kV)进行颈动脉 CTA 是可行的,可达到非常低的剂量水平,而整体图像质量与使用自动管电压选择的方案相当。