Eller A, Wuest W, Kramer M, May M, Schmid A, Uder M, Lell M M
From the Department of Radiology, University Erlangen, Erlangen, Germany.
AJNR Am J Neuroradiol. 2014 Feb;35(2):237-41. doi: 10.3174/ajnr.A3659. Epub 2013 Aug 1.
CTA is considered the imaging modality of choice in evaluating the supraaortic vessels in many institutions, but radiation exposure remains a matter of concern. The objective of the study was to evaluate a fully automated, attenuation-based kilovolt selection algorithm in carotid CTA in respect to radiation dose and image quality compared with a standard 120-kV protocol.
Ninety-eight patients were included: 53 examinations (patient age, 66 ± 12 years) were performed by use of automated adaption of tube potential (80-140 kV) on the basis of the attenuation profile of the scout scan (study group), and 45 examinations (patient age, 67 ± 11 years) were performed by use of a standard 120-kV protocol (control group). CT dose index volume and dose-length product were recorded from the examination protocol. Image quality was assessed by ROI measurements and calculations of SNR and contrast-to-noise ratio. Subjective image quality was evaluated by 2 observers with the use of a 4-point scale (3, excellent; 0, not diagnostic).
Subjective image quality was rated as "excellent" or "good" in all examinations (study group, 2.8; control group, 2.8). The algorithm automatically selected 100 kV in 47% and 80 kV in 34%; 120 kV was retained in 19%. An elevation to 140 kV did not occur. Compared with the control group, overall CT dose index volume reduction was 33.7%; overall dose-length product reduction was 31.5%. In the low-kilovolt scans, image noise and mean attenuation of ROIs inside the carotid arteries were significantly higher than in 120-kV scans, resulting in a constant or increased (80-kV group) contrast-to-noise ratio.
The attenuation-based, kilovolt selection algorithm enables a dose reduction of >30% in carotid artery CTA while maintaining contrast-to-noise ratio and subjective image quality at adequate levels.
在许多机构中,CT血管造影(CTA)被认为是评估主动脉弓上血管的首选成像方式,但辐射暴露仍是一个令人担忧的问题。本研究的目的是评估一种基于衰减的全自动千伏选择算法在颈动脉CTA中的辐射剂量和图像质量,并与标准的120 kV协议进行比较。
纳入98例患者:53例检查(患者年龄66±12岁)采用基于定位像扫描衰减曲线的管电压自动适配(80 - 140 kV)进行(研究组),45例检查(患者年龄67±11岁)采用标准的120 kV协议进行(对照组)。从检查协议中记录CT剂量指数容积(CTDIvol)和剂量长度乘积(DLP)。通过感兴趣区(ROI)测量以及信噪比(SNR)和对比噪声比(CNR)的计算来评估图像质量。由2名观察者使用4分制(3分,优秀;0分,不能诊断)对主观图像质量进行评估。
所有检查的主观图像质量均被评为“优秀”或“良好”(研究组评分为2.8;对照组评分为2.8)。该算法自动选择100 kV的占47%,选择80 kV的占34%;选择120 kV的占19%。未出现升至140 kV的情况。与对照组相比,总体CTDIvol降低了33.7%;总体DLP降低了31.5%。在低千伏扫描中,颈动脉内ROI的图像噪声和平均衰减显著高于120 kV扫描,导致对比噪声比保持不变或增加(80 kV组)。
基于衰减的千伏选择算法可使颈动脉CTA的剂量降低超过30%,同时将对比噪声比和主观图像质量维持在适当水平。