Zhou Kehua, Faraz Aniqa, Magotra Minoti, Tahir Muhammad
Catholic Health Internal Medicine Training Program, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
Mercy Hospital of Buffalo, Buffalo, New York, USA.
BMJ Case Rep. 2019 Jul 10;12(7):e230310. doi: 10.1136/bcr-2019-230310.
Primary gastric squamous cell carcinoma (SCC) is rare, and the simultaneous infection has not been reported in the literature. Here, we presented a patient with concurrent gastritis and primary gastric SCC. A 54-year-old Hispanic man presented with diarrhoea, chills, night sweats and weight loss of 16 lbs for the previous 6 weeks. Abdominal CT revealed large exophytic mass from the stomach infiltrating multiple organs. Biopsy was performed and histology showed squamoid features. Immunohistochemistry stain was positive for p40, CK5/6, CK7 and Helicobacter type organisms. Patient was diagnosed with primary gastric SCC and has been receiving chemotherapy. We also reviewed the diagnosis, prognosis and treatment of primary gastric SCC.
原发性胃鳞状细胞癌(SCC)较为罕见,文献中尚未报道过同时感染的情况。在此,我们报告了一例同时患有胃炎和原发性胃SCC的患者。一名54岁的西班牙裔男性,出现腹泻、寒战、盗汗,且在过去6周内体重减轻了16磅。腹部CT显示胃有巨大外生性肿块,侵犯多个器官。进行了活检,组织学显示有鳞状特征。免疫组化染色p40、CK5/6、CK7及幽门螺杆菌属生物呈阳性。患者被诊断为原发性胃SCC,一直在接受化疗。我们还回顾了原发性胃SCC的诊断、预后及治疗。