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盐沼盐杆菌模式菌株的基因组序列与实验室菌株NRC-1和R1的基因组序列密切相关。

The Genome Sequence of the Halobacterium salinarum Type Strain Is Closely Related to That of Laboratory Strains NRC-1 and R1.

作者信息

Pfeiffer Friedhelm, Marchfelder Anita, Habermann Bianca, Dyall-Smith Mike L

机构信息

Computational Biology Group, Max Planck Institute of Biochemistry, Martinsried, Germany

Biology II, Ulm University, Ulm, Germany.

出版信息

Microbiol Resour Announc. 2019 Jul 11;8(28):e00429-19. doi: 10.1128/MRA.00429-19.

Abstract

High-coverage long-read sequencing of the type strain (91-R6) revealed a 2.17-Mb chromosome and two large plasmids (148 and 102 kb). Population heterogeneity and long repeats were observed. Strain 91-R6 and laboratory strain R1 showed 99.63% sequence identity in common chromosomal regions and only 38 strain-specific segments. This information resolves the previously uncertain relationship between type and laboratory strains.

摘要

对模式菌株(91-R6)进行的高覆盖率长读长测序显示,其染色体大小为2.17 Mb,还有两个大质粒(148 kb和102 kb)。观察到了群体异质性和长重复序列。91-R6菌株与实验室菌株R1在共同的染色体区域显示出99.63%的序列同一性,仅有38个菌株特异性片段。这些信息解决了之前模式菌株与实验室菌株之间不确定的关系。

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