Popa P, Gheonea D I, Săftoiu A, Calița M
Department of Gastroenterology, Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy of Craiova, Craiova, Romania.
Curr Health Sci J. 2019 Jan-Mar;45(1):5-18. doi: 10.12865/CHSJ.45.01.01. Epub 2019 Mar 31.
Colonoscopy is long time the most preferred method for CRC screening along with diagnosis and treatment for a range of colon diseases. Based on its difficulty in visualizing precursor CRC lesions, mostly those located on the right colon, this method can be subject of improvement. The colonoscopy quality can be influenced by many factors such as colon preparation, retraction time, the colonoscopists medical training and knowledges as well as the performance of endoscopy equipment. The bad quality of colonoscopy will result in the emergence of interval cancers defined, based on the author, as cancers that appear at 3-5 years up to 10 years from the colonoscopy procedure. Interval cancers have predominantly incriminated both the colonoscopy quality and the clinician competences and less the tumor biology. Subsequently there were set quality indicators of colonoscopy in order to raise the quality of the exploration. Among the important indicators, proving their utility in studies, the ADR (adenoma detection rate) is most commonly used along with PDR (polyp detection rate) and APC (adenoma per colonoscopy). Following the purpose of obtaining a higher colonoscopy quality the medical units should keep in check all indicators. Furthermore, there should be an active involvement in an additional training of non-conforming medical personnel or even restrain of practice, given the medical legal actions that have interval cancers as a main cause.
长期以来,结肠镜检查一直是结直肠癌(CRC)筛查以及一系列结肠疾病诊断和治疗的首选方法。鉴于其在可视化结直肠癌前体病变(主要是位于右结肠的病变)方面存在困难,该方法有待改进。结肠镜检查的质量会受到多种因素影响,如肠道准备情况、退镜时间、结肠镜医师的医学培训和知识水平以及内镜设备的性能。结肠镜检查质量不佳会导致出现间期癌,根据作者定义,间期癌是指在结肠镜检查后3至5年甚至长达10年出现的癌症。间期癌主要归咎于结肠镜检查质量和临床医生的能力,而较少归因于肿瘤生物学特性。随后设定了结肠镜检查的质量指标,以提高检查质量。在众多重要指标中,已在研究中证明其效用的有腺瘤检出率(ADR),它与息肉检出率(PDR)和每次结肠镜检查腺瘤数(APC)一样常用。为了获得更高的结肠镜检查质量,医疗单位应监控所有指标。此外,鉴于间期癌是主要医疗法律诉讼原因,对于不符合要求的医务人员应积极安排额外培训,甚至限制其执业。