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在半硬性输尿管镜检查中使用改良输尿管鞘治疗上段输尿管大结石,结石清除率高。

Use of a modified ureteral access sheath in semi-rigid ureteroscopy to treat large upper ureteral stones is associated with high stone free rates.

作者信息

AlSmadi Jad Khaled, Li Xiaohang, Zeng Guohua

机构信息

Department of Urology, Minimally Invasive Surgery Center, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Guangdong Key Laboratory of Urology, Guangzhou, China.

出版信息

Asian J Urol. 2019 Jul;6(3):217-221. doi: 10.1016/j.ajur.2018.12.008. Epub 2019 Jan 7.

Abstract

OBJECTIVE

To examine differences in outcomes of semi-rigid ureteroscopy (URS) with or without a modified-ureteral-access-sheath (mUAS) to treat large upper ureteral stones.

METHODS

Patients with single, radio-opaque large upper ureteral stone (≥10 mm) treated using semi-rigid URS between August 2013 and October 2016 were retrospectively evaluated. The stone-free status was determined from Kidney-ureter-bladder (KUB) X-ray films taken on postoperative Day 1 and after 1 month.

RESULTS

Of 103 patients meeting inclusion criteria, 43 (41.75%) and 60 (58.25%) were treated with semi-rigid URS with and without mUAS, respectively. The immediate stone-free rate (SFR) for the mUAS group was significantly higher than the non-mUAS group (40 [93.0%] 46 [76.7%];  = 0.033). The SFR at 1 month was also high for patients treated using mUAS, but not statistically different from patients not treated with mUAS (41 [95.3%] mUAS 51 [85.0%] non-mUAS;  = 0.115). Auxiliary procedure rates were significantly lower for mUAS patients compared to non-mUAS patients (2 [4.7%] 14 [23.3%];  = 0.01). There were no significant differences in surgical duration and hospital stays, and the overall complication rates were statistically similar for mUAS patients compared to non-mUAS patients (1 [2.3%] 3 [5.0%];  = 0.638).

CONCLUSION

Application of mUAS to treat large upper ureteric stones was associated with higher immediate SFR and final SFR, and lower auxiliary procedure rates relative to patients treated without use of mUAS. Moreover, the use of mUAS did not lengthen operation duration or hospital stays.

摘要

目的

探讨在治疗上段输尿管大结石时,使用或不使用改良输尿管鞘(mUAS)的半硬性输尿管镜检查(URS)的疗效差异。

方法

回顾性评估2013年8月至2016年10月期间使用半硬性URS治疗单发、不透X线的上段输尿管大结石(≥10mm)的患者。根据术后第1天和1个月后拍摄的腹部平片(KUB)确定结石清除情况。

结果

103例符合纳入标准的患者中,分别有43例(41.75%)和60例(58.25%)接受了使用和未使用mUAS的半硬性URS治疗。mUAS组的即刻结石清除率(SFR)显著高于未使用mUAS组(40例[93.0%]对46例[76.7%];P = 0.033)。使用mUAS治疗的患者1个月时的SFR也较高,但与未使用mUAS治疗的患者相比无统计学差异(41例[95.3%]使用mUAS对51例[85.0%]未使用mUAS;P = 0.115)。mUAS患者的辅助手术率显著低于未使用mUAS的患者(2例[4.7%]对14例[23.3%];P = 0.01)。手术时间和住院时间无显著差异,mUAS患者与未使用mUAS患者的总体并发症发生率在统计学上相似(1例[2.3%]对3例[5.0%];P = 0.638)。

结论

与未使用mUAS治疗的患者相比,应用mUAS治疗上段输尿管大结石的即刻SFR和最终SFR更高,辅助手术率更低。此外,使用mUAS并未延长手术时间或住院时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9af2/6595155/e74b4971991c/gr1.jpg

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