Dat Truong Quang, Giang Le Nguyen Huong, Bao Pham Van, Tuyen Nguyen Thi Hong
Binh Dinh Medical College, Vietnam.
Binh Dinh Province's Center for Disease Control and Prevention, Vietnam.
AIMS Public Health. 2019 May 23;6(2):184-194. doi: 10.3934/publichealth.2019.2.184. eCollection 2019.
The study was conducted to estimate the goiter prevalence, and the median urine iodine concentrations among schoolchildren aged 8-10 in Binh Dinh province, Vietnam.
A school-based cross-sectional survey was carried out from May 2016 to May 2017. A multistage, proportional-to-population-size sampling method with 30 clusters was used. The children were examined by palpation for the presence or absence of goiter based on the criteria of the World Health Organization (WHO), the United Nations Children's Fund (UNICEF), International Council for the Control of Iodine Deficiency (ICCIDD); urinary iodine was determined in microplates by a modification of the Sandell-Kolthoff reaction. The Chi-square test was used to compare prevalences, and the Chi-square test for trend was employed to assess the trend of goiter prevalence and urine iodine levels by age and economic-social areas.
1800 pupils from 8 to 10 years old including 900 males and 900 females were examined and 300 among them were tested for the urinary iodine concentration (UIC). The prevalence of goiter among schoolchildren was 6.6%. The prevalence of goiter tended to increase in areas with disadvantaged conditions, among which the urban areas occupied the lowest prevalence (5%) while the mountainous areas and Midland took the highest (8.8%) (the -value of 0.0193). The median UIC of the study group was 159.9 µg/L; the 25 and 75 percentile value was 103 µg/L and 230.2 µg/L, respectively.
According to the WHO/UNICEF/ICCIDD classification, the goiter prevalence indicated that some regions of Binh Dinh province appeared to be slightly affected by iodine deficiency. These have characterized an important public health challenge, highlighting the need to eliminate iodine deficiency disorders in these areas.
本研究旨在评估越南平定省8至10岁学童的甲状腺肿患病率及尿碘浓度中位数。
2016年5月至2017年5月开展了一项基于学校的横断面调查。采用多阶段、按人口规模比例抽样方法，抽取30个群组。依据世界卫生组织（WHO）、联合国儿童基金会（UNICEF）、国际碘缺乏病控制理事会（ICCIDD）的标准，通过触诊检查儿童是否存在甲状腺肿；采用改良的桑德尔 - 科尔托夫反应在微孔板中测定尿碘。使用卡方检验比较患病率，并采用趋势卡方检验评估甲状腺肿患病率和尿碘水平随年龄及经济社会区域的变化趋势。
对1800名8至10岁的学生进行了检查，其中包括900名男性和900名女性，对其中300人进行了尿碘浓度（UIC）检测。学童甲状腺肿患病率为6.6%。在条件不利的地区，甲状腺肿患病率呈上升趋势，其中城市地区患病率最低（5%），山区和中部地区患病率最高（8.8%）（P值为0.0193）。研究组的尿碘浓度中位数为159.9µg/L；第25和第75百分位数分别为103µg/L和230.2µg/L。
根据WHO/UNICEF/ICCIDD分类，甲状腺肿患病率表明平定省部分地区似乎受到碘缺乏的轻微影响。这构成了一项重要的公共卫生挑战，凸显了在这些地区消除碘缺乏病的必要性。
