Laboratory of Neurological Diseases, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Epilepsy Behav. 2019 Nov;100(Pt B):106363. doi: 10.1016/j.yebeh.2019.05.051. Epub 2019 Jul 9.
Social functions are commonly impaired in people with epilepsy who are at increased risk of experiencing altered social cognition, communication problems, and interpersonal difficulties. Several factors are implicated, including developmental delay, seizure-related factors, somatic and psychiatric comorbidities, antiepileptic drugs (AEDs), and - not least - the effects of stigma. The variable interaction of all these factors can explain the differing pictures observed in the various epilepsy phenotypes but is also a source of interindividual variability depending on the strength of the effects of each factor on social cognition. This article is part of the Special Issue "Epilepsy and social cognition across the lifespan.
社交功能通常在癫痫患者中受损,他们面临着更高的改变社交认知、沟通问题和人际困难的风险。一些因素被牵涉其中,包括发育迟缓、与癫痫发作相关的因素、躯体和精神共病、抗癫痫药物(AEDs),以及 - 最不容忽视的 - 耻辱感的影响。所有这些因素的可变相互作用可以解释在各种癫痫表型中观察到的不同情况,但也是个体间变异性的一个来源,取决于每个因素对社交认知的影响的强度。本文是特刊“癫痫和全生命周期的社会认知”的一部分。