From the Center for Family and Community Medicine, Columbia University Irving Medical Center, New York, NY (SXL, KP, RGY); St. John's University College of Pharmacy and Health Sciences, Queens, NY (KP); New York Presbyterian Hospital, New York, NY (RGY).
J Am Board Fam Med. 2019 Jul-Aug;32(4):614-618. doi: 10.3122/jabfm.2019.04.180311.
Increased drug overdose deaths have become a serious public health problem. Primary care providers prescribe about 50% all opioid medications. This study examined opioids prescribing during primary visits to patients with a pain-depression dyad and patient demographic characteristics associated with opioids prescribing.
This study analyzed data from the 2014 to 2015 National Ambulatory Medical Care Survey and included primary care visits by adult patients (aged 18 years or older) with noncancer pain.
An opioid medication was prescribed in 26.4% (95% CI, 22.6% to 30.6%) of the primary care visits by patients with noncancer pain. Opioid medications were more likely to be prescribed during visits by patients with a pain and depression dyad (adjusted odds ratios [AOR] = 1.8; 95% CI, 1.4 to 2.4). Narcotic analgesics were more likely to be prescribed during visits by patients aged 46 to 64 years; by male patients or non-Hispanic white patients.
DISCUSSION/CONCLUSIONS: Pain-depression dyad is associated with higher odds of opioids prescribing during primary care visits. Future studies are needed to understand the complexity of these factors and identify effective strategies to prevent opioids addiction and overdose among patients with pain and depression.
药物过量死亡人数的增加已成为一个严重的公共卫生问题。初级保健提供者开具的阿片类药物约占所有阿片类药物的 50%。本研究调查了在有疼痛-抑郁双重问题的患者的初级就诊期间开具阿片类药物的情况,以及与开具阿片类药物相关的患者人口统计学特征。
本研究分析了 2014 年至 2015 年全国门诊医疗调查的数据,包括患有非癌症疼痛的成年患者(年龄在 18 岁或以上)的初级保健就诊。
在有非癌症疼痛的初级保健就诊中,有 26.4%(95%CI,22.6%至 30.6%)的患者开具了阿片类药物。在有疼痛和抑郁双重问题的患者就诊中,更有可能开具阿片类药物(调整后的优势比[OR] = 1.8;95%CI,1.4 至 2.4)。在 46 岁至 64 岁的患者就诊中,更有可能开具麻醉性镇痛药;在男性患者或非西班牙裔白人患者就诊中,更有可能开具阿片类药物。
讨论/结论:疼痛-抑郁双重问题与初级保健就诊中开具阿片类药物的几率较高有关。未来的研究需要了解这些因素的复杂性,并确定预防有疼痛和抑郁的患者阿片类药物成瘾和过量的有效策略。