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一名婴儿由罕见病原体引起的医院获得性肺炎和败血症及文献综述

Nosocomial pneumonia and sepsis caused by a rare organism in an infant and a review of literature.

作者信息

Ramaswamy Viraraghavan Vadakkencherry, Gummadapu Sanghamitra, Suryanarayana Nori

机构信息

Neonatology, Nori Multispeciality Hospital, Vijayawada, Andhra Pradesh, India.

出版信息

BMJ Case Rep. 2019 Jul 11;12(7):e229854. doi: 10.1136/bcr-2019-229854.

DOI:10.1136/bcr-2019-229854
PMID:31300600
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6626479/
Abstract

A late preterm male infant of 36 weeks gestation and a birth weight of 2100 g was admitted on day 35 of life with complaints of respiratory distress and lethargy. He was diagnosed as a case of sepsis screen positive culture negative sepsis and was managed with respiratory support and intravenous antibiotics for 10 days. The infant improved clinically and was on spoon feeds by day 14 of admission. On day 14 of admission, he developed new-onset respiratory distress and was diagnosed as a case of nosocomial pneumonia based on chest radiography findings. The blood culture grew a rare organism and a diagnosis of sepsis was also made. The antibiotics were tailored as per the blood culture sensitivity pattern and the infant had clinical improvement in the next 72 hours.

摘要

一名孕36周、出生体重2100克的晚期早产儿在出生后第35天因呼吸窘迫和嗜睡入院。他被诊断为脓毒症筛查阳性、培养阴性脓毒症,接受了呼吸支持和静脉抗生素治疗10天。婴儿临床症状有所改善,入院第14天时开始用勺子喂食。入院第14天,他出现新发呼吸窘迫,根据胸部X光检查结果被诊断为医院获得性肺炎。血培养培养出一种罕见微生物,也诊断为脓毒症。根据血培养药敏结果调整了抗生素,婴儿在接下来的72小时内临床症状有所改善。

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本文引用的文献

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Int J Antimicrob Agents. 2017 Jan;49(1):118-119. doi: 10.1016/j.ijantimicag.2016.10.001. Epub 2016 Oct 20.
2
First Reported Case of Ventilator-Associated Pneumonia and Sepsis Caused by Cedecea lapagei in a Brazilian Neonatal Intensive Care Unit.巴西新生儿重症监护病房首例由拉氏西地西菌引起的呼吸机相关性肺炎和脓毒症报告病例
J Pediatric Infect Dis Soc. 2017 Jun 1;6(2):209-210. doi: 10.1093/jpids/piw077.
3
Cedecea davisae bacteremia in a neutropenic patient with acute myeloid leukemia.中性粒细胞减少症的急性髓系白血病患者发生戴维斯西地西菌血症。
J Infect. 2011 Jul;63(1):83-5. doi: 10.1016/j.jinf.2011.04.007. Epub 2011 Apr 27.
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Cedecea lapagei bacteremia following cement-related chemical burn injury.水泥相关化学烧伤后出现拉帕吉西地西菌血症。
Burns. 2008 Dec;34(8):1205-7. doi: 10.1016/j.burns.2007.09.001. Epub 2008 May 7.
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Leg ulcer and bacteremia due to Cedecea davisae.戴维斯西地西菌所致腿部溃疡和菌血症
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