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An Effective Epigenetic-PARP Inhibitor Combination Therapy for Breast and Ovarian Cancers Independent of BRCA Mutations.
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Talazoparib in Patients with a Germline BRCA-Mutated Advanced Breast Cancer: Detailed Safety Analyses from the Phase III EMBRACA Trial.
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PARP Inhibitors in the Treatment of Early Breast Cancer: The Step Beyond?
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DNA damage response in breast cancer and its significant role in guiding novel precise therapies.
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Advancements and challenges in triple-negative breast cancer: a comprehensive review of therapeutic and diagnostic strategies.
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DNA repair pathways in breast cancer: from mechanisms to clinical applications.
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Epigenetic Regulation in Breast Cancer: Insights on Epidrugs.
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PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer.
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Maintenance Olaparib in Patients with Newly Diagnosed Advanced Ovarian Cancer.
N Engl J Med. 2018 Dec 27;379(26):2495-2505. doi: 10.1056/NEJMoa1810858. Epub 2018 Oct 21.
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Homology-Directed Repair and the Role of BRCA1, BRCA2, and Related Proteins in Genome Integrity and Cancer.
Annu Rev Cancer Biol. 2018 Mar;2:313-336. doi: 10.1146/annurev-cancerbio-030617-050502. Epub 2017 Dec 1.
8
Advances in the use of PARP inhibitor therapy for breast cancer.
Drugs Context. 2018 Aug 8;7:212540. doi: 10.7573/dic.212540. eCollection 2018.
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Talazoparib in Patients with Advanced Breast Cancer and a Germline BRCA Mutation.
N Engl J Med. 2018 Aug 23;379(8):753-763. doi: 10.1056/NEJMoa1802905. Epub 2018 Aug 15.
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The evolving landscape of predictive biomarkers of response to PARP inhibitors.
J Clin Invest. 2018 May 1;128(5):1727-1730. doi: 10.1172/JCI120388. Epub 2018 Apr 16.

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