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日本滋贺县南部地区院外心脏骤停患者中,配备医师的救护车与可电击心律和不可电击心律患者预后之间的关联:一项回顾性观察研究

Association between physician-staffed ambulances and patient prognoses after out-of-hospital cardiac arrests with respect to shockable and non-shockable rhythms: a retrospective observational study in a southern area of Shiga Prefecture Japan.

作者信息

Kato Fumitaka, Fujino Kazunori, Shiomi Naoto, Eguchi Yutaka

机构信息

Department of Emergency and Critical Care Medicine Saiseikai Shiga Hospital Ritto Shiga Japan.

Department of Critical and Intensive Care Medicine Shiga University of Medical Science Otsu Shiga Japan.

出版信息

Acute Med Surg. 2019 Mar 12;6(3):265-273. doi: 10.1002/ams2.405. eCollection 2019 Jul.

Abstract

AIM

Out-of-hospital cardiac arrests (OHCA) are a significant public health problem; to improve patients' prognoses, various interventions, such as providing physician-staffed ambulances, have been implemented. We aimed to examine whether physician-staffed ambulances were associated with patients' prognoses after OHCA with respect to first-monitored rhythms.

METHODS

This retrospective observational study was undertaken between 1 September 2011 and 31 December 2015, using data based on Utstein-style guidelines. We extracted data on age, sex, first-monitored rhythm (shockable or non-shockable), presence of a witness, bystander cardiopulmonary resuscitation, time from call to arrival at the scene, out-of-hospital adrenaline administration, out-of-hospital intubation, return of spontaneous circulation before arrival at the hospital, and survival and neurological outcomes 30 days after OHCA, according to cerebral performance categories. We undertook logistic regression analyses to assess the association between physician-staffed ambulances and patients' prognoses.

RESULTS

A total of 882 OHCA patients were eligible for this study. Physician-staffed ambulances attended to 164 OHCA patients. Multivariable analysis found that in non-shockable rhythm patients, physician-staffed ambulances significantly improved good neurological outcome (odds ratio, 3.65; 95% confidence interval [CI], 1.28-10.50;  = 0.02), return of spontaneous circulation before arrival at the hospital (odds ratio, 2.68; 95% CI, 1.62-4.42;  < 0.001), and 30-day survival (odds ratio, 2.90; 95% CI, 1.30-6.45;  = 0.009). However, physician-staffed ambulances were not associated with patient prognoses in shockable rhythm patients.

CONCLUSION

Despite our study's limitations, physician-staffed ambulances might be associated with good neurological outcomes in non-shockable rhythm patients. Our observations could provide more appropriate prehospital treatment options for OHCA patients.

摘要

目的

院外心脏骤停(OHCA)是一个重大的公共卫生问题;为改善患者预后,已实施了各种干预措施,如配备医生的救护车。我们旨在研究配备医生的救护车与OHCA患者首次监测心律后的预后是否相关。

方法

本回顾性观察性研究于2011年9月1日至2015年12月31日进行,使用基于Utstein风格指南的数据。我们提取了以下数据:年龄、性别、首次监测心律(可电击或不可电击)、是否有目击者、旁观者心肺复苏情况、呼叫至到达现场的时间、院外肾上腺素给药情况、院外插管情况、到达医院前自主循环恢复情况以及OHCA后30天的生存情况和根据脑功能分类的神经学结局。我们进行了逻辑回归分析,以评估配备医生的救护车与患者预后之间的关联。

结果

共有882例OHCA患者符合本研究条件。配备医生的救护车接诊了164例OHCA患者。多变量分析发现,在不可电击心律患者中,配备医生的救护车显著改善了良好神经学结局(优势比,3.65;95%置信区间[CI],1.28 - 10.50;P = 0.02)、到达医院前自主循环恢复情况(优势比,2.68;95%CI,1.62 - 4.42;P < 0.001)以及30天生存率(优势比,2.90;95%CI,1.30 - 6.45;P = 0.009)。然而,配备医生的救护车与可电击心律患者的预后无关。

结论

尽管本研究存在局限性,但配备医生的救护车可能与不可电击心律患者的良好神经学结局相关。我们的观察结果可为OHCA患者提供更合适的院前治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95c9/6603314/efdec419a1e3/AMS2-6-265-g001.jpg

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