抗 N- 甲基-D-天冬氨酸受体脑炎在 HIV 感染青少年中的表现及文献复习
Anti-NMDA-receptor Encephalitis in an Adolescent With HIV Infection and Review of the Literature.
机构信息
From the Infectious Diseases, Immunology, Allergy and Rheumatology, Queensland Children's Hospital, South Brisbane.
Greenslopes Private Hospital, Brisbane, Australia.
出版信息
Pediatr Infect Dis J. 2019 Aug;38(8):e169-e171. doi: 10.1097/INF.0000000000002338.
Anti-N-Methyl-D-Aspartate-receptor encephalitis is the most common antibody-mediated autoimmune encephalopathy. A HIV-infected African boy presented with subacute psychosis as manifestation of anti-N-Methyl-D-Aspartate-receptor encephalitis. Intravenous immunoglobulin and corticosteroids induced complete remission. Although this is the first pediatric case described, 5 adult cases have been reported. The role of HIV in the etiology of this autoimmune condition requires further exploration.
抗 N-甲基-D-天冬氨酸受体脑炎是最常见的抗体介导的自身免疫性脑炎。一名感染 HIV 的非洲男孩表现为亚急性精神病，这是抗 N-甲基-D-天冬氨酸受体脑炎的表现。静脉注射免疫球蛋白和皮质类固醇诱导完全缓解。尽管这是首例儿科病例描述，但已有 5 例成人病例报告。HIV 在这种自身免疫性疾病病因中的作用需要进一步探索。
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