Bürger R A, Gerharz C D, Küppers P, Engelmann U
Department of Urology, University Hospital Mainz, Federal Republic of Germany.
Urol Res. 1988;16(2):127-31. doi: 10.1007/BF00261970.
A comparative study was undertaken to investigate the application of a specially adapted microsurgical Neodymium Yag Laser system with a wavelength of 1,319 microns and a CO2 laser system for laser assisted microvascular end-to-end anastomosis (LAMA) of the rat femoral artery. Conventionally sutured anastomoses served as controls. Postoperative investigations included patency tests, light microscopy and tensile strength measurements. Both laser systems seem to be equally suitable for LAMA: The patency rates do not differ from those of sutured anastomoses and formation of microscopically small aneurysms occurred predominantly in control animals and only once in laser groups. The clamp time needed for LAMA was half the time that was needed for sutured anastomoses. Wound healing in all groups was similar with less fibrotic reactions and less foreign body granulomas in laser groups. At all intervals tensile strength was significantly higher for sutured anastomoses while differences between the CO2- and the ND: Yag-laser groups were not statistically significant. Potential applications in urology include microvascular anastomoses in erectile dysfunction, pediatric and reconstructive urology.
进行了一项比较研究，以调查一种专门改装的波长为1319微米的钕钇铝石榴石（Neodymium Yag）激光系统和二氧化碳激光系统在大鼠股动脉激光辅助微血管端端吻合术（LAMA）中的应用。传统缝合的吻合术作为对照。术后检查包括通畅性测试、光学显微镜检查和拉伸强度测量。两种激光系统似乎同样适用于LAMA：通畅率与缝合吻合术的通畅率没有差异，显微镜下小动脉瘤的形成主要发生在对照动物中，在激光组中仅出现过一次。LAMA所需的夹闭时间是缝合吻合术所需时间的一半。所有组的伤口愈合情况相似，激光组的纤维化反应和异物肉芽肿较少。在所有时间间隔内，缝合吻合术的拉伸强度明显更高，而二氧化碳激光组和钕钇铝石榴石激光组之间的差异没有统计学意义。在泌尿外科的潜在应用包括勃起功能障碍、小儿泌尿外科和重建泌尿外科中的微血管吻合术。
