Basu S, Wang S, Robertazzi R, Grubbs P E, Jacobowitz I, Rose D, Acinapura A J, Cunningham J N
Department of Surgery, Maimonides Medical Center, Brooklyn, NY 11219.
J Vasc Surg. 1988 Mar;7(3):420-2.
We compared the mechanical integrity of microvascular anastomoses created with a carbon dioxide (CO2) laser with conventional suture anastomoses. Seventy rat femoral artery segments (35 lased and 35 sutured) were harvested at 1, 24, and 72 hours, and 1, 3, 6, and 12 weeks postoperatively. These segments were subjected to increasingly higher in vitro intraluminal hydrostatic pressures (bursting pressure). Conventionally sutured anastomoses exhibited significantly increased ability (p less than 0.05) to withstand greater bursting pressures than the laser-welded tissue up to 3 weeks postoperatively. After the third postoperative week, the laser anastomoses demonstrated increased bursting pressures compared with the conventional anastomoses. At the end of the 12-week period both groups demonstrated an ability to withstand supraphysiologic pressures in excess of 2000 mm Hg.
我们比较了使用二氧化碳（CO2）激光创建的微血管吻合口与传统缝合吻合口的机械完整性。在术后1小时、24小时、72小时以及1周、3周、6周和12周时，采集了70个大鼠股动脉段（35个激光吻合的和35个缝合的）。这些动脉段承受逐渐升高的体外腔内静水压力（破裂压力）。在术后长达3周的时间里，传统缝合的吻合口比激光焊接组织表现出显著更强的承受更高破裂压力的能力（p小于0.05）。术后第三周后，与传统吻合口相比，激光吻合口的破裂压力有所增加。在12周结束时，两组均表现出承受超过2000毫米汞柱的超生理压力的能力。
