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术后心房颤动与预测指数的高分相关。

Postoperative atrial fibrillation is associated with higher scores on predictive indices.

机构信息

Department of Clinical Cardiology, Instituto Cardiovascular de Buenos Aires, Buenos Aires, Argentina.

Department of Cardiac Surgery, Instituto Cardiovascular de Buenos Aires, Buenos Aires, Argentina.

出版信息

J Thorac Cardiovasc Surg. 2019 Jun;157(6):2279-2286. doi: 10.1016/j.jtcvs.2018.10.091. Epub 2018 Oct 28.

Abstract

OBJECTIVE

To compare the performance of the CHADS VASc, POAF, and HATCH scoring systems to predict new-onset atrial fibrillation after cardiac surgery.

METHODS

We conducted a single-center cohort study, performing a retrospective analysis of prospectively collected data. The study included consecutive patients undergoing cardiac surgery between January 2010 and December 2016. The primary outcome was the development of new-onset postoperative atrial fibrillation during hospitalization.

RESULTS

A total of 3113 patients underwent cardiac surgery during the study period: coronary artery bypass graft surgery (45%), valve replacement (24%), combined procedure (revascularization-valve surgery) (15%), and other procedures (16%). Twenty-one percent (n = 654) presented postoperative atrial fibrillation. Median scores in patients with postoperative atrial fibrillation were significantly higher (P < .001). The CHAD2DS2-VASc score demonstrated greater discriminative ability to predict the event (C-statistic, 0.77; 95% confidence interval [CI], 0.75-0.79) versus the POAF score and the HATCH score (C-statistic, 0.71; 95% CI, 0.69-0.73 and C-statistic, 0.70; 95% CI, 0.67-0.72, respectively). All 3 scores presented good calibration according to the Hosmer-Lemeshow test univariate and multivariable analysis demonstrated that the 3 scores were independent predictors of postoperative atrial fibrillation: CHA2DS2-VASc score odds ratio 1.87 (95% CI, 1.64-2.13), POAF score odds ratio 1.18 (95% CI, 1.01-1.36), and HATCH score odds ratio 1.62 (95% CI, 1.37-1.92).

CONCLUSIONS

The POAF, CHA2DS2-VASc, and HATCH scoring systems showed good discrimination and calibration to predict postoperative atrial fibrillation in patients undergoing cardiac surgery. Among them, the CHA2DS2-Vasc score presented the best discriminative ability for postoperative atrial fibrillation and has the advantage of being easy to calculate.

摘要

目的

比较 CHADS2VASc、POAF 和 HATCH 评分系统预测心脏手术后新发心房颤动的性能。

方法

我们进行了一项单中心队列研究,对前瞻性收集的数据进行回顾性分析。该研究纳入了 2010 年 1 月至 2016 年 12 月期间接受心脏手术的连续患者。主要结局是住院期间新发术后心房颤动的发生。

结果

在研究期间,共有 3113 名患者接受了心脏手术:冠状动脉旁路移植术(45%)、瓣膜置换术(24%)、联合手术(血运重建-瓣膜手术)(15%)和其他手术(16%)。21%(n=654)出现术后心房颤动。患有术后心房颤动的患者的中位数评分明显更高(P<.001)。CHAD2DS2-VASc 评分在预测该事件方面具有更高的区分能力(C 统计量,0.77;95%置信区间[CI],0.75-0.79),而 POAF 评分和 HATCH 评分的 C 统计量分别为 0.71(95%CI,0.69-0.73)和 0.70(95%CI,0.67-0.72)。所有 3 个评分根据 Hosmer-Lemeshow 检验均具有良好的校准性。单变量和多变量分析表明,3 个评分均为术后心房颤动的独立预测因子:CHA2DS2-VASc 评分比值比 1.87(95%CI,1.64-2.13),POAF 评分比值比 1.18(95%CI,1.01-1.36),HATCH 评分比值比 1.62(95%CI,1.37-1.92)。

结论

POAF、CHA2DS2-VASc 和 HATCH 评分系统在预测心脏手术后患者的术后心房颤动方面具有良好的区分度和校准度。其中,CHA2DS2-VASc 评分对术后心房颤动具有最佳的区分能力,并且易于计算。

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