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三级心脏中心心脏手术后新发房颤的四种预测评分评估

An Evaluation of Four Predictive Scores for New Onset Atrial Fibrillation After Cardiac Surgery in a Tertiary Cardiac Centre.

作者信息

Chang Shantel, van der Merwe Madeleen, Zaka Ammar, Gupta Aashray, He Cheng, Stroebel Andrie

机构信息

Griffith University, School of Medicine and Dentistry, Gold Coast, Queensland, Australia.

Department of Cardiothoracic Surgery, Gold Coast University Hospital, Gold Coast, Queensland, Australia.

出版信息

ANZ J Surg. 2025 Jul-Aug;95(7-8):1394-1399. doi: 10.1111/ans.70229. Epub 2025 Jun 23.

Abstract

BACKGROUND

Postoperative atrial fibrillation (POAF) is a common complication after cardiac surgery, leading to increased mortality, morbidity, and length of stay. Various predictive indices have been validated to identify patients at risk of developing POAF. This study aimed to compare the discriminative ability of four bedside indices that predict POAF in cardiac surgical patients.

METHOD

A total of 2465 consecutive patients who underwent cardiac surgery at an Australian tertiary hospital between 29 December 2015, and 31 December 2022, were retrospectively analysed. Exclusion criteria included pre-existing atrial fibrillation and transcatheter interventions. The area under the receiver-operating characteristic curve (AUC-ROC) analysis and Hosmer-Lemeshow calibration were performed to compare discriminative abilities. A logistic regression model was constructed to evaluate independent risk factors for developing POAF.

RESULTS

Older patients (aged > 69) were more likely to develop POAF compared to younger age groups (p < 0.001). The Atrial Fibrillation Risk Index, CHADS-VASC, HATCH and POAF scores had weak discrimination and demonstrated poor predictive ability in this cohort (AUC-ROC 0.49, 0.49, 0.50, 0.52, respectively).

CONCLUSION

Although previously validated in various cohorts, the four bedside predictive indices demonstrated poor discriminative ability and limited generalizability to our tertiary-hospital cohort.

摘要

背景

术后房颤(POAF)是心脏手术后常见的并发症,会导致死亡率、发病率增加以及住院时间延长。多种预测指标已被证实可用于识别有发生POAF风险的患者。本研究旨在比较四种预测心脏手术患者发生POAF的床边指标的鉴别能力。

方法

回顾性分析了2015年12月29日至2022年12月31日期间在澳大利亚一家三级医院接受心脏手术的2465例连续患者。排除标准包括既往存在房颤和经导管干预。进行受试者操作特征曲线下面积(AUC-ROC)分析和Hosmer-Lemeshow校准以比较鉴别能力。构建逻辑回归模型以评估发生POAF的独立危险因素。

结果

与年轻年龄组相比,老年患者(年龄>69岁)发生POAF的可能性更高(p<0.001)。房颤风险指数、CHADS-VASC、HATCH和POAF评分的鉴别能力较弱,在该队列中显示出较差的预测能力(AUC-ROC分别为0.49、0.49、0.50、0.52)。

结论

尽管这四种床边预测指标先前在不同队列中得到了验证,但在我们的三级医院队列中,它们的鉴别能力较差且普遍性有限。

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