Shah Sidra, Chahil Vipanpreet, Battisha Ayman, Haq Syed, Kalra Dinesh K
Division of Cardiology, Department of Medicine, University of Louisville, Louisville, KY 40202, USA.
Biomedicines. 2024 Sep 1;12(9):1968. doi: 10.3390/biomedicines12091968.
Atrial fibrillation (AF) in the postoperative phase is a manifestation of numerous factors, including surgical stress, anesthetic effects, and underlying cardiovascular conditions. The resultant cardiac hyperactivity can induce new onset or exacerbate existing AF. A common phenomenon, postoperative atrial fibrillation (POAF) affects nearly 40% of patients and is associated with longer hospitalization stays, and increased mortality, heart failure, stroke, and healthcare costs. Areas of controversy in POAF include whether to anticoagulate patients who have short-lived POAF, especially given their higher bleeding risk in the postoperative period, and the identification of patients who would benefit the most from preventive drug therapy for POAF. This review discusses the pathophysiology and management of POAF, and strategies to reduce its occurrence.
术后房颤(AF)是多种因素的表现,包括手术应激、麻醉效果和潜在的心血管疾病。由此产生的心脏过度活动可诱发新发房颤或加重现有房颤。术后房颤(POAF)是一种常见现象,影响近40%的患者,与住院时间延长、死亡率增加、心力衰竭、中风及医疗费用增加相关。POAF存在争议的领域包括对于短暂性POAF患者是否进行抗凝治疗,尤其是考虑到他们在术后出血风险较高,以及确定哪些患者能从POAF预防性药物治疗中获益最大。本综述讨论了POAF的病理生理学、管理以及降低其发生率的策略。