Kuroda R, Nakatani J, Kitano M, Yamada Y, Yorimae A
Department of Neurosurgery, Kinki University, Osaka, Japan.
Appl Neurophysiol. 1987;50(1-6):420-4. doi: 10.1159/000100751.
Dorsal root entry zone (DREZ) lesions were made in the cervical dorsal horn in cat and monkey. Terminal degeneration was observed in the lateral cervical nucleus in cat and contralateral VPL in monkey by Fink-Heimer stain. WGA-HRP was injected in the cervical dorsal horn of cat and retrograde labelled cells were observed mainly in the raphe nucleus, parabrachial nucleus, locus coeruleus, Kölliker-Fuse nucleus, Eddinger-Westphal nucleus, and hypothalamic area, indicating that these descending fiber systems are involved by the DREZ lesion. The functional role of these fibers in regard to deafferentation pain relief seems now to be open to discussion.
在猫和猴的颈髓背角制作背根入髓区（DREZ）损伤。通过芬克-海默染色法，在猫的外侧颈核和猴的对侧腹后外侧核（VPL）观察到终末退变。将小麦胚芽凝集素-辣根过氧化物酶（WGA-HRP）注入猫的颈髓背角，逆行标记的细胞主要见于中缝核、臂旁核、蓝斑、 Kölliker-Fuse核、动眼神经副核和下丘脑区域，表明这些下行纤维系统受到DREZ损伤的影响。现在，这些纤维在去传入性疼痛缓解方面的功能作用似乎有待探讨。
