Powers S K, Barbaro N M, Levy R M
Division of Neurological Surgery, University of North Carolina, Chapel Hill.
Appl Neurophysiol. 1988;51(2-5):243-54. doi: 10.1159/000099969.
Pain relief was evaluated in 40 patients with various types of deafferentation pain that were treated with dorsal root entry zone (DREZ) lesions produced with microsurgical lasers. Good long-term pain relief was evident in some paraplegics and in all patients with brachial plexus avulsion. Several other small subgroups of patients benefited from laser DREZ lesions as well. Pain associated with arachnoiditis and peripheral nerve injury or neuropathy did not respond to laser DREZ lesioning. Based upon the smaller lesion dimensions produced with the lasers, it is proposed that interruption of impulses in the tract of Lissauer may be a mechanism of pain control in patients that responded to laser DREZ lesions.
对40例患有各种类型去传入性疼痛的患者进行了疼痛缓解评估，这些患者接受了显微外科激光制造的背根入区（DREZ）损伤治疗。在一些截瘫患者和所有臂丛神经撕脱患者中，长期疼痛缓解效果明显。其他几个小亚组的患者也从激光DREZ损伤中获益。与蛛网膜炎以及周围神经损伤或神经病变相关的疼痛对激光DREZ损伤无反应。基于激光产生的较小损伤范围，有人提出，Lissauer束中冲动的中断可能是对激光DREZ损伤有反应的患者疼痛控制的一种机制。
