Ranjan Redoy, Adhikary Dipannita, Mandal Sabita, Saha Sanjoy Kumar, Hasan Kamrul, Adhikary Asit Baran
Department of Cardiac Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
Department of Public Health, North South University, Dhaka, Bangladesh.
JRSM Cardiovasc Dis. 2019 Jul 4;8:2048004019862125. doi: 10.1177/2048004019862125. eCollection 2019 Jan-Dec.
European System for Cardiac Operative Risk Evaluation (EuroSCORE) was developed to identify patients who may have a greater postoperative risk for adverse effects following adult cardiac surgery. This study evaluated the discriminatory potential of using the EuroSCORE system in predicting the early, as well as late, postoperative outcomes following coronary artery bypass graft surgery in Bangladesh.
A total of 865 patients who underwent isolated coronary artery bypass graft surgery were evaluated with the EuroSCORE risk scoring system. Moreover, we also compared the discriminatory potentials between the EuroSCORE II and the original logistic EuroSCORE.
Operative mortality was best predicted by EuroSCORE II (area under the curve (AUC) 0.863, Brier score 0.030) compared to the original logistic EuroSCORE (AUC 0.849, Brier score 0.033). However, the overall expected-to-observed mortality ratio for EuroSCORE II was 1.1, whereas the observed ratio for the original logistic EuroSCORE was 1.7. EuroSCORE II was predictive of an intensive care unit stay of five days or more (AUC 0.786), prolonged inotropes use (AUC 0.746), stroke (AUC 0.646), de novo dialysis (AUC 0.810), and low output syndrome (AUC 0.715). Moreover, a high EuroSCORE II quintile significantly predicted the risk for late mortality (p < 0.0001).
EuroSCORE has an important role in predicting the early, as well as late, postoperative outcomes following coronary artery bypass surgery. However, the performance of EuroSCORE II is significantly better than the original logistic EuroSCORE in predicting postoperative morbidity and mortality after isolated coronary artery bypass graft surgery among Bangladeshi patients.
欧洲心脏手术风险评估系统(EuroSCORE)旨在识别成年心脏手术后可能出现更大术后不良反应风险的患者。本研究评估了在孟加拉国冠状动脉旁路移植术后使用EuroSCORE系统预测早期和晚期术后结局的鉴别潜力。
使用EuroSCORE风险评分系统对总共865例行单纯冠状动脉旁路移植术的患者进行评估。此外,我们还比较了EuroSCORE II与原始逻辑EuroSCORE之间的鉴别潜力。
与原始逻辑EuroSCORE(曲线下面积(AUC)0.849,Brier评分0.033)相比,EuroSCORE II对手术死亡率的预测效果最佳(AUC 0.863,Brier评分0.030)。然而,EuroSCORE II的总体预期与观察到的死亡率之比为1.1,而原始逻辑EuroSCORE的观察到的比率为1.7。EuroSCORE II可预测重症监护病房住院5天或更长时间(AUC 0.786)、延长使用血管活性药物(AUC 0.746)、中风(AUC 0.646)、新发透析(AUC 0.810)和低心排血量综合征(AUC 0.715)。此外,EuroSCORE II的高五分位数显著预测了晚期死亡风险(p<0.0001)。
EuroSCORE在预测冠状动脉旁路移植术后的早期和晚期术后结局方面具有重要作用。然而,在预测孟加拉国患者单纯冠状动脉旁路移植术后的术后发病率和死亡率方面,EuroSCORE II的表现明显优于原始逻辑EuroSCORE。