Varon Jack, Baron Rebecca M
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 75 Francis St, Boston, MA 02115, USA.
Ther Adv Infect Dis. 2019 Jul 5;6:2049936119856517. doi: 10.1177/2049936119856517. eCollection 2019 Jan-Dec.
Sepsis is a life-threatening syndrome of a dysregulated host response to infection. Despite advances in diagnosis and treatment, sepsis remains a significant cause of morbidity and mortality. Many aspects of the diagnosis and clinical management of sepsis require further study and remain controversial. This review aims to summarize relevant literature and controversies regarding the evaluation and management of sepsis and septic shock.
脓毒症是宿主对感染反应失调的一种危及生命的综合征。尽管在诊断和治疗方面取得了进展,但脓毒症仍然是发病和死亡的重要原因。脓毒症的诊断和临床管理的许多方面需要进一步研究,并且仍然存在争议。本综述旨在总结关于脓毒症和脓毒性休克评估与管理的相关文献及争议。