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ALPPS一期手术中未来肝剩余部分门静脉或肝静脉重建——我们能将界限推到多远?

Future liver remnant portal or hepatic vein reconstruction at stage I of ALPPS-How far can we push the boundaries?

作者信息

Schlegel Andrea, Sakuraoka Yuhki, Kalisvaart Marit, Coldham Chris, Isaac John, Muiesan Paolo

机构信息

The Liver Unit, Queen Elizabeth Hospital Birmingham, University of Birmingham, Birmingham, United Kingdom.

NIHR Liver Biomedical Research Unit, University Hospitals Birmingham, Birmingham, United Kingdom.

出版信息

J Surg Oncol. 2019 Sep;120(4):654-660. doi: 10.1002/jso.25618. Epub 2019 Jul 16.

Abstract

Preservation of the future liver remnant (FLR) vascular integrity has always been considered crucial to achieving successful liver growths after major hepatectomies. Most surgeons appeared therefore reluctant to combine stage I of associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) with vascular reconstructions. Here we describe a case series, where we combine parenchymal transection and venous in- or outflow reconstruction of the FLR at stage I of ALPPS. In addition, the cold flush of the FLR or delayed portal vein embolization is applied in selected cases.

摘要

保留未来肝残余(FLR)的血管完整性一直被认为对于在大肝切除术后实现成功的肝脏再生至关重要。因此,大多数外科医生似乎不愿意将联合肝脏分隔和门静脉结扎分期肝切除术(ALPPS)的第一阶段与血管重建相结合。在此,我们描述了一个病例系列,在该系列中我们在ALPPS的第一阶段将实质横断与FLR的静脉流入或流出道重建相结合。此外,在部分病例中应用了FLR的冷灌注或延迟门静脉栓塞。

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