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种族差异与贫困相关的全膝关节置换失败。

Racial Disparities in Total Knee Replacement Failure As Related to Poverty.

机构信息

Hospital for Special Surgery, New York, New York.

New York University, New York.

出版信息

Arthritis Care Res (Hoboken). 2019 Nov;71(11):1488-1494. doi: 10.1002/acr.24028.

Abstract

OBJECTIVE

To determine whether racial disparities in total knee replacement (TKR) failure are explained by poverty.

METHODS

Black and white New York state residents, enrolled in a prospective single-institution TKR registry January 1, 2008 to February 6, 2012, who underwent primary unilateral TKR (n = 4,062) were linked to the New York Statewide Planning and Research Cooperative System database (January 1, 2008 to December 31, 2014) to capture revisions performed at outside institutions. Patients were linked by geocoded addresses to residential census tracts. Multivariable Cox regression was used to assess predictors of TKR revision. Multivariable logistic regression was used to analyze predictors of TKR failure, defined as TKR revision in New York state ≤2 years after surgery, or as Hospital for Special Surgery (HSS) TKR quality of life score "not improved" or "worsened" 2 years after surgery.

RESULTS

The mean ± SD age was 68.4 ± 10 years, 64% of patients were female, 8% lived in census tracts with >20% of the population under the poverty line, and 9% were black. Median follow-up time was 5.3 years. A total of 3% of patients (122 of 4,062) required revision a median 454 days (interquartile range 215-829) after surgery. TKR revision risk was higher in blacks than whites, with a hazard ratio of 1.69 (95% confidence interval 1.01-2.81), but in multivariable analysis, only younger age, male sex, and constrained prosthesis were predictors of TKR revision. TKR failure occurred in 200 of 2,832 cases (7%) with 2-year surveys. Risk factors for TKR failure were non-osteoarthritis TKR indication, low surgeon volume, and low HSS Expectations Survey score, but not black race. Community poverty was not associated with TKR revision or failure.

CONCLUSION

There was a trend toward higher TKR revision risk in blacks, but poverty did not modify the relationship between race and TKR revision or failure.

摘要

目的

确定在全膝关节置换术(TKR)失败中是否存在种族差异,这种差异是否可以用贫困来解释。

方法

2008 年 1 月 1 日至 2012 年 2 月 6 日,在纽约州的一家单机构 TKR 注册中心接受初次单侧 TKR 的黑人和白人居民(n=4062)被纳入研究,并链接到纽约州全州规划和研究合作系统数据库(2008 年 1 月 1 日至 2014 年 12 月 31 日),以捕捉在其他机构进行的修订。患者通过地理编码地址与居住人口普查区相关联。多变量 Cox 回归用于评估 TKR 修正的预测因素。多变量逻辑回归用于分析 TKR 失败的预测因素,TKR 失败定义为手术后 2 年内纽约州内的 TKR 修正,或手术后 2 年内医院特殊外科医院(HSS)TKR 生活质量评分“无改善”或“恶化”。

结果

患者的平均年龄±标准差为 68.4±10 岁,64%为女性,8%居住在人口普查区,其人口中有超过 20%生活在贫困线以下,9%为黑人。中位随访时间为 5.3 年。共有 3%的患者(4062 例中的 122 例)在手术后中位数 454 天(四分位距 215-829)后需要进行修正。与白人相比,黑人的 TKR 修正风险更高,风险比为 1.69(95%置信区间为 1.01-2.81),但在多变量分析中,只有年龄较小、男性和受限型假体是 TKR 修正的预测因素。在 2832 例中有 200 例(7%)发生了 2 年调查的 TKR 失败。TKR 失败的危险因素是非骨关节炎 TKR 指征、低手术量和低 HSS 期望调查评分,但不是黑人种族。社区贫困与 TKR 修正或失败无关。

结论

黑人的 TKR 修正风险有上升趋势,但贫困并没有改变种族与 TKR 修正或失败之间的关系。

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