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患者种族与全膝关节置换术后手术结果:一项大型区域性数据库分析。

Patient race and surgical outcomes after total knee arthroplasty: an analysis of a large regional database.

机构信息

Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

出版信息

Arthritis Care Res (Hoboken). 2013 Mar;65(3):414-20. doi: 10.1002/acr.21834.

Abstract

OBJECTIVE

To examine racial differences in surgical complications, mortality, and revision rates after total knee arthroplasty.

METHODS

We studied patients undergoing primary total knee arthroplasty using 2001-2007 Pennsylvania Health Care Cost Containment Council data. We conducted bivariate analyses to assess the risk of complications such as myocardial infarction, venous thromboembolism, wound infections, and failure of prosthesis, as well as 30-day and 1-year overall mortality after elective total knee arthroplasty, between racial groups. We estimated Kaplan-Meier 1- and 5-year surgical revision rates, and fit multivariable Cox proportional hazards models to compare surgical revision by race, incorporating 5 years of followup. We adjusted for patient age, sex, length of hospital stay, surgical risk of death, type of health insurance, hospital surgical volume, and hospital teaching status.

RESULTS

In unadjusted analyses, there were no significant differences by racial group for either overall 30-day or in-hospital complication rates, or 30-day and 1-year mortality rates. Adjusted Cox models incorporating 5 years of followup showed an increased risk of revisions for African American patients (hazard ratio [HR] 1.39, 95% confidence interval [95% CI] 1.08-1.80), younger patients (HR 2.30, 95% CI 1.96-2.69), and lower risk for female patients (HR 0.81, 95% CI 0.71-0.92).

CONCLUSION

In this sample of patients who underwent knee arthroplasty, we found no significant racial differences in major complication rates or mortality. However, African American patients, younger patients, and male patients all had significantly higher rates of revision based on 5 years of followup.

摘要

目的

研究全膝关节置换术后手术并发症、死亡率和翻修率的种族差异。

方法

我们使用 2001-2007 年宾夕法尼亚州医疗保健费用控制委员会的数据研究了接受初次全膝关节置换术的患者。我们进行了双变量分析,以评估种族间并发症(如心肌梗死、静脉血栓栓塞、伤口感染和假体失败)的风险,以及择期全膝关节置换术后 30 天和 1 年总死亡率,在种族群体之间。我们估计了 Kaplan-Meier 1 年和 5 年的手术翻修率,并拟合多变量 Cox 比例风险模型,比较种族之间的手术翻修率,纳入 5 年的随访。我们调整了患者年龄、性别、住院时间、手术死亡风险、医疗保险类型、医院手术量和医院教学地位。

结果

在未调整的分析中,种族组之间在总体 30 天或住院内并发症发生率,或 30 天和 1 年死亡率方面均无显著差异。纳入 5 年随访的调整 Cox 模型显示,非裔美国患者的翻修风险增加(风险比 [HR] 1.39,95%置信区间 [95%CI] 1.08-1.80),年轻患者(HR 2.30,95%CI 1.96-2.69)和低风险女性患者(HR 0.81,95%CI 0.71-0.92)。

结论

在接受膝关节置换术的患者样本中,我们未发现主要并发症发生率或死亡率存在显著的种族差异。然而,在基于 5 年随访的情况下,非裔美国患者、年轻患者和男性患者的翻修率都明显更高。

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