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Int J Infect Dis. 2018 May;70:30-35. doi: 10.1016/j.ijid.2018.02.009. Epub 2018 Feb 21.
3
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4
Ageing with HIV: do comorbidities and polymedication drive treatment optimization?HIV 感染者老龄化:合并症和多药物治疗是否会影响治疗优化?
HIV Med. 2017 Jul;18(6):395-401. doi: 10.1111/hiv.12441. Epub 2016 Oct 7.
5
One-year mortality of HIV-positive patients treated for rifampicin- and isoniazid-susceptible tuberculosis in Eastern Europe, Western Europe, and Latin America.东欧、西欧和拉丁美洲接受利福平及异烟肼敏感型结核病治疗的HIV阳性患者的一年死亡率。
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Lancet HIV. 2015 Oct;2(10):e438-44. doi: 10.1016/S2352-3018(15)00137-X. Epub 2015 Aug 11.
7
Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.全球、地区和国家按年龄、性别划分的 240 种死因的全死因和特定死因死亡率,1990-2013 年:2013 年全球疾病负担研究的系统分析。
Lancet. 2015 Jan 10;385(9963):117-71. doi: 10.1016/S0140-6736(14)61682-2. Epub 2014 Dec 18.
8
Adjudicated morbidity and mortality outcomes by age among individuals with HIV infection on suppressive antiretroviral therapy.接受抑制性抗逆转录病毒治疗的HIV感染者按年龄划分的已判定发病和死亡结局。
PLoS One. 2014 Apr 11;9(4):e95061. doi: 10.1371/journal.pone.0095061. eCollection 2014.
9
The interplay between CD4 cell count, viral load suppression and duration of antiretroviral therapy on mortality in a resource-limited setting.在资源有限的环境下,CD4 细胞计数、病毒载量抑制和抗逆转录病毒治疗持续时间之间的相互作用对死亡率的影响。
Trop Med Int Health. 2013 May;18(5):619-31. doi: 10.1111/tmi.12079. Epub 2013 Feb 18.
10
All-cause mortality in hospitalized HIV-infected patients at an acute tertiary care hospital with a comprehensive outpatient HIV care program in New York City in the era of highly active antiretroviral therapy (HAART).在高效抗逆转录病毒治疗(HAART)时代,纽约市一家急性三级护理医院的综合性门诊艾滋病毒护理项目中住院感染艾滋病毒患者的全因死亡率。
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[三级医院中HIV患者的住院情况及死亡原因]

[Hospital admission and mortality causes of HIV patients in a third level hospital].

作者信息

Asensi-Diez R, Fernández-Cuerva C, Alcaraz Sánchez J J, Muñoz-Castillo I

机构信息

Rocío Asensi-Diez, Hospital Regional Universitario de Málaga. Avenida de Carlos Haya s/n. CP.29010. Málaga. Spain.

出版信息

Rev Esp Quimioter. 2019 Aug;32(4):317-326. Epub 2019 Jul 15.

PMID:31310085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6719647/
Abstract

OBJECTIVE

The aim of this study is to describe the HIV population admitted to a tertiary level hospital and analyze hospital admission and mortality causes during hospitalization.

METHODS

Observational, retrospective study carried out in a third level Hospital. Inclusion criteria: Patients ≥18 years with a prescription of ART and diagnosis of HIV known or discovered during admission. It was accepted hospital ward discharge diagnose as hospitalization causes. Clinical, analytical outcomes as well as causes of mortality were collected.

RESULTS

Among 162 hospitalized HIV infected, 128 met the inclusion criteria, 8 of those were diagnosed as naive HIV patients. 79.7% were male; Age 50.29 ± 9.81 years. The main reasons for hospital admissions (38.3%) were certain infectious and parasitic diseases (ICD-10 Classification) and more specifically human immunodeficiency virus [HIV] disease represented 24,1% of whole hospitalizations. Mortality rates of ≥18 years HIV patients that were admitted to hospital during 2016-2017 were the 13.52%. The main causes of death were certain infectious and parasitic diseases followed by malignancies.

CONCLUSIONS

Our results emphasize the need of intensifying the HIV early diagnosis as well as Pneumocystis jirovecii primary prophylaxis. Insist on ART adherence from infectology follow-up appointment and pharmacy care consultations, educate clinics on ART treatment prescription during hospital admission as well as requesting viral and CD4 lymphocytes loads to every HIV admitted patients.

摘要

目的

本研究旨在描述一家三级医院收治的艾滋病毒感染人群,并分析住院期间的入院原因和死亡原因。

方法

在一家三级医院开展观察性、回顾性研究。纳入标准:年龄≥18岁、正在接受抗逆转录病毒治疗(ART)且在入院时确诊或新发现感染艾滋病毒的患者。将医院病房出院诊断作为入院原因。收集临床、分析结果以及死亡原因。

结果

在162名住院的艾滋病毒感染者中,128名符合纳入标准,其中8名被诊断为初治艾滋病毒患者。79.7%为男性;年龄50.29±9.81岁。入院的主要原因(38.3%)是某些感染性和寄生虫病(国际疾病分类第10版),更具体地说,人类免疫缺陷病毒[HIV]病占全部住院病例的24.1%。2016 - 2017年期间入院的≥18岁艾滋病毒患者的死亡率为13.52%。主要死亡原因是某些感染性和寄生虫病,其次是恶性肿瘤。

结论

我们的结果强调需要加强艾滋病毒的早期诊断以及耶氏肺孢子菌的一级预防。坚持在感染病随访预约和药房护理咨询中强调抗逆转录病毒治疗的依从性,在入院时对临床医生进行抗逆转录病毒治疗处方教育,并对每名入院的艾滋病毒患者进行病毒载量和CD4淋巴细胞计数检测。