Asensi-Diez R, Fernández-Cuerva C, Alcaraz Sánchez J J, Muñoz-Castillo I
Rocío Asensi-Diez, Hospital Regional Universitario de Málaga. Avenida de Carlos Haya s/n. CP.29010. Málaga. Spain.
Rev Esp Quimioter. 2019 Aug;32(4):317-326. Epub 2019 Jul 15.
The aim of this study is to describe the HIV population admitted to a tertiary level hospital and analyze hospital admission and mortality causes during hospitalization.
Observational, retrospective study carried out in a third level Hospital. Inclusion criteria: Patients ≥18 years with a prescription of ART and diagnosis of HIV known or discovered during admission. It was accepted hospital ward discharge diagnose as hospitalization causes. Clinical, analytical outcomes as well as causes of mortality were collected.
Among 162 hospitalized HIV infected, 128 met the inclusion criteria, 8 of those were diagnosed as naive HIV patients. 79.7% were male; Age 50.29 ± 9.81 years. The main reasons for hospital admissions (38.3%) were certain infectious and parasitic diseases (ICD-10 Classification) and more specifically human immunodeficiency virus [HIV] disease represented 24,1% of whole hospitalizations. Mortality rates of ≥18 years HIV patients that were admitted to hospital during 2016-2017 were the 13.52%. The main causes of death were certain infectious and parasitic diseases followed by malignancies.
Our results emphasize the need of intensifying the HIV early diagnosis as well as Pneumocystis jirovecii primary prophylaxis. Insist on ART adherence from infectology follow-up appointment and pharmacy care consultations, educate clinics on ART treatment prescription during hospital admission as well as requesting viral and CD4 lymphocytes loads to every HIV admitted patients.
本研究旨在描述一家三级医院收治的艾滋病毒感染人群,并分析住院期间的入院原因和死亡原因。
在一家三级医院开展观察性、回顾性研究。纳入标准:年龄≥18岁、正在接受抗逆转录病毒治疗(ART)且在入院时确诊或新发现感染艾滋病毒的患者。将医院病房出院诊断作为入院原因。收集临床、分析结果以及死亡原因。
在162名住院的艾滋病毒感染者中,128名符合纳入标准,其中8名被诊断为初治艾滋病毒患者。79.7%为男性;年龄50.29±9.81岁。入院的主要原因(38.3%)是某些感染性和寄生虫病(国际疾病分类第10版),更具体地说,人类免疫缺陷病毒[HIV]病占全部住院病例的24.1%。2016 - 2017年期间入院的≥18岁艾滋病毒患者的死亡率为13.52%。主要死亡原因是某些感染性和寄生虫病,其次是恶性肿瘤。
我们的结果强调需要加强艾滋病毒的早期诊断以及耶氏肺孢子菌的一级预防。坚持在感染病随访预约和药房护理咨询中强调抗逆转录病毒治疗的依从性,在入院时对临床医生进行抗逆转录病毒治疗处方教育,并对每名入院的艾滋病毒患者进行病毒载量和CD4淋巴细胞计数检测。