Department of Obstetrics & Gynaecology, First affiliated hospital of Xi'an Jiaotong University, China.
Xi'an Jiaotong University, Xi'an, China.
Placenta. 2019 Sep 15;85:69-73. doi: 10.1016/j.placenta.2019.07.003. Epub 2019 Jul 5.
Placental abruption is a serious pregnancy complication that causes maternal and neonatal mortality and morbidity. Whether maternal and neonatal outcomes differ between patients who concurrently presented with preeclampsia and those who did not, have not been fully investigated.
A total number of 158 patients with placental abruption were included. Of them, 66 concurrently had preeclampsia. Maternal and neonatal characteristics including delivery weeks, time of onset and birthweight as well as the grade of placental abruption were collected and analysed.
The time at diagnosis of placental abruption in patients who concurrently presented preeclampsia was significantly earlier than that in patients who did not. The number of patients with grade III placental abruption was significantly higher in patients who concurrently presented with preeclampsia, compared to patients who did not. The odds ratio of an increase in grade III placental abruption in patients who concurrently presented preeclampsia was 5.27 (95%CL: 2.346, 12.41), compared to patients who did not. The numbers of infants who were born pre-term and the numbers of stillbirth/neonatal deaths as well as the number of fetal distress were significantly higher in patients who concurrently presented with preeclampsia, compared to patients who did not. The fetal birthweight was significantly lower in patients who concurrently presented with preeclampsia compared to patients who did not.
Our study demonstrates that women with preeclampsia experiencing placental abruption had worse maternal, fetal and neonatal outcomes, compared to women experiencing placental abruption alone.
胎盘早剥是一种严重的妊娠并发症，可导致孕产妇和新生儿死亡和发病。同时患有子痫前期和不患有子痫前期的胎盘早剥患者的母婴和新生儿结局是否存在差异，尚未得到充分研究。
共纳入 158 例胎盘早剥患者，其中 66 例同时患有子痫前期。收集和分析了产妇和新生儿的特征，包括分娩周数、发病时间和出生体重以及胎盘早剥的分级。
并发子痫前期的胎盘早剥患者的诊断时间明显早于不并发子痫前期的患者。并发子痫前期的患者中，胎盘早剥 III 级的患者数量明显多于不并发子痫前期的患者。与不并发子痫前期的患者相比，并发子痫前期的患者胎盘早剥 III 级的发生几率增加了 5.27 倍（95%CL：2.346，12.41）。并发子痫前期的患者中早产儿、死胎/新生儿死亡和胎儿窘迫的数量明显多于不并发子痫前期的患者。与不并发子痫前期的患者相比，并发子痫前期的患者胎儿出生体重明显降低。
本研究表明，与单纯发生胎盘早剥的患者相比，同时患有子痫前期的患者母婴和新生儿结局更差。
