脑膜瘤压迫硬脑膜静脉窦所致视乳头水肿
Papilloedema from Dural Venous Sinus Compression by Meningiomas.
作者信息
Hartmann Alexander J P W, Latting Michelle W, Lee Michael S, Moster Mark L, Saindane Amit M, Newman Nancy J, Biousse Valérie
机构信息
Departments of Ophthalmology and Neurology, University of Rochester School of Medicine, Rochester, New York, USA.
Department of Neuro-Ophthalmology, Wills Eye Hospital, Philadelphia, Pennsylvania, USA.
出版信息
Neuroophthalmology. 2018 Oct 17;43(3):171-179. doi: 10.1080/01658107.2018.1524499. eCollection 2019 Jun.
Intracranial mass lesions may cause intracranial hypertension secondary to venous hypertension when they compress the dural venous sinuses (DVS) and may present with isolated papilloedema, mimicking idiopathic intracranial hypertension. We report a series of 16 patients with isolated papilloedema related to meningiomas compressing the DVS seen from 2012 to 2016 at three institutions. Correct diagnosis was delayed in 10/16 patients and treatment required a multidisciplinary approach, often with multiple sequential interventions, including combinations of acetazolamide, cerebrospinal fluid-shunt, optic nerve sheath fenestration, surgical resection of the meningioma, radiation therapy, and endovascular venous stenting. Two patients also received anticoagulation for venous thrombosis secondary to venous sinus compression.
颅内占位性病变压迫硬脑膜静脉窦（DVS）时，可继发静脉高压导致颅内高压，并可能仅表现为视乳头水肿，酷似特发性颅内高压。我们报告了2012年至2016年在三家机构中见到的一系列16例因脑膜瘤压迫DVS而出现孤立性视乳头水肿的患者。16例患者中有10例诊断延误，治疗需要多学科方法，通常需要多次序贯干预，包括乙酰唑胺、脑脊液分流、视神经鞘开窗、脑膜瘤手术切除、放射治疗和血管内静脉支架置入术联合应用。两名患者还因静脉窦受压继发静脉血栓形成而接受了抗凝治疗。
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