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环丙沙星治疗期间的止血情况。

Haemostasis during treatment with ciprofloxacin.

作者信息

Ziemen M, Shah P M, Breddin K

机构信息

Center of Internal Medicine, J. W. Goethe University, Frankfurt am Main.

出版信息

Infection. 1988;16 Suppl 1:S65-8. doi: 10.1007/BF01650512.

DOI:10.1007/BF01650512
PMID:3131252
Abstract

The effects of ciprofloxacin, a new quinolone derivative with high activity on gram-negative aerobic bacteria and gram-positive cocci, on haemostasis were investigated in 11 healthy volunteers. No influence on platelet function was detectable. In some cases a slight reduction in antithrombin III activity was observed at the end of the therapy. No other changes were evident in the plasma coagulation parameters.

摘要

环丙沙星是一种对革兰氏阴性需氧菌和革兰氏阳性球菌具有高活性的新型喹诺酮衍生物,我们在11名健康志愿者身上研究了它对止血的影响。未检测到对血小板功能有影响。在某些情况下,治疗结束时观察到抗凝血酶III活性略有降低。血浆凝血参数无其他明显变化。

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Haemostasis during treatment with ciprofloxacin.环丙沙星治疗期间的止血情况。
Infection. 1988;16 Suppl 1:S65-8. doi: 10.1007/BF01650512.
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本文引用的文献

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Influence of penicillin on the coagulation of blood with especial reference to certain dental operations.青霉素对血液凝固的影响,特别涉及某些牙科手术。
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Prolonged bleeding time during azlocillin therapy.阿洛西林治疗期间出血时间延长。
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Carbenicillin and penicillin G inhibit platelet function in vitro by impairing the interaction of agonists with the platelet surface.羧苄青霉素和青霉素G在体外通过损害激动剂与血小板表面的相互作用来抑制血小板功能。
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6
In vitro activity of ciprofloxacin, norfloxacin and nalidixic acid.环丙沙星、诺氟沙星和萘啶酸的体外活性。
Eur J Clin Microbiol. 1983 Apr;2(2):111-5. doi: 10.1007/BF02001575.
7
Effects of moxalactam on blood coagulation and platelet function.羟羧氧酰胺菌素对血液凝固及血小板功能的影响。
Rev Infect Dis. 1982 Nov-Dec;4 Suppl:S546-54. doi: 10.1093/clinids/4.supplement_3.s546.
8
Hemorrhage, diarrhea, and superinfection associated with the use of moxalactam.使用羟羧氧酰胺菌素相关的出血、腹泻和二重感染。
J Infect Dis. 1983 Jan;147(1):171-2. doi: 10.1093/infdis/147.1.171.
9
Coagulopathy associated with the use of moxalactam.
JAMA. 1982 Sep 3;248(9):1100.
10
Gastrointestinal bleeding due to vitamin K deficiency in patients on parenteral cefamandole.接受胃肠外头孢孟多治疗的患者因维生素K缺乏导致的胃肠道出血
Lancet. 1980 Jan 5;1(8158):39-40. doi: 10.1016/s0140-6736(80)90571-1.