Haemostasis during treatment with ciprofloxacin.

The effects of ciprofloxacin, a new quinolone derivative with high activity on gram-negative aerobic bacteria and gram-positive cocci, on haemostasis were investigated in 11 healthy volunteers. No influence on platelet function was detectable. In some cases a slight reduction in antithrombin III activity was observed at the end of the therapy. No other changes were evident in the plasma coagulation parameters.