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枯草芽孢杆菌中L-阿拉伯糖利用组成型突变体的分离

Isolation of constitutive mutants for L-arabinose utilization in Bacillus subtilis.

作者信息

Sá-Nogueira I, Paveia H, de Lencastre H

机构信息

Laboratório de Genética Molecular, Instituto Gulbenkian de Ciência, Oeiras, Portugal.

出版信息

J Bacteriol. 1988 Jun;170(6):2855-7. doi: 10.1128/jb.170.6.2855-2857.1988.

DOI:10.1128/jb.170.6.2855-2857.1988
PMID:3131313
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC211213/
Abstract

Constitutive mutants for L-arabinose utilization were isolated from Bacillus subtilis 168T+ and showed resistance to D-fucose, a nonmetabolizable analog of L-arabinose. The mutations that conferred the constitutive phenotype (Arac) were mapped between cysB and hisA. All the mutants showed an isomerase activity which was reduced to 50 to 70% in the presence of L-arabinose and to 10% in the presence of glucose.

摘要

从枯草芽孢杆菌168T+中分离出利用L-阿拉伯糖的组成型突变体，这些突变体对L-阿拉伯糖的非代谢类似物D-岩藻糖具有抗性。赋予组成型表型（Arac）的突变位于cysB和hisA之间。所有突变体均表现出一种异构酶活性，在L-阿拉伯糖存在下该活性降低至50%至70%，在葡萄糖存在下降低至10%。

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Isolation of constitutive mutants for L-arabinose utilization in Bacillus subtilis.枯草芽孢杆菌中L-阿拉伯糖利用组成型突变体的分离
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2
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引用本文的文献

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4
Modulation of Bacillus subtilis catabolite repression by transition state regulatory protein AbrB.过渡态调节蛋白AbrB对枯草芽孢杆菌分解代谢物阻遏的调控
J Bacteriol. 1994 Apr;176(7):1903-12. doi: 10.1128/jb.176.7.1903-1912.1994.
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J Bacteriol. 1989 Jul;171(7):4088-91. doi: 10.1128/jb.171.7.4088-4091.1989.

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C R Acad Hebd Seances Acad Sci D. 1967 Jun 5;264(23):2683-6.
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D-Fucose as a gratuitous inducer of the L-arabinose operon in strains of Escherichia coli B-r mutant in gene araC.D-岩藻糖作为阿拉伯糖操纵子在大肠杆菌B-r araC基因突变株中的 gratuitous诱导剂 。 （注：这里“gratuitous”不太明确准确意思，可根据具体专业背景进一步确认准确含义来完善译文表述）
J Bacteriol. 1971 Jul;107(1):79-86. doi: 10.1128/jb.107.1.79-86.1971.
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Hyperinducibility as a result of mutation in structural genes and self-catabolite repression in the ara operon.由于结构基因突变导致的超诱导性以及阿拉伯糖操纵子中的自我分解代谢物阻遏。
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