头颈部癌症患者放疗后颞下颌关节紊乱：临床发现和患者自述症状。
Temporomandibular disorder in head and neck cancer patients undergoing radiotherapy: Clinical findings and patient-reported symptoms.
机构信息
Department of Otorhinolaryngology, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden.
Clinic of Orofacial Pain, Sahlgrenska Academy and Public Dental Health, Gothenburg, Sweden.
出版信息
Head Neck. 2019 Oct;41(10):3570-3576. doi: 10.1002/hed.25878. Epub 2019 Jul 16.
BACKGROUND
The aim of this study was to investigate how common temporomandibular disorder (TMD) symptoms are among head and neck cancer (HNC) patients before and after oncological treatment.
METHODS
Eighty-nine patients with HNC receiving radiotherapy were enrolled in the study. Patients were examined before radiotherapy and at 6 and 12 months after radiotherapy to evaluate the function and tenderness of the temporomandibular jaw and the muscles of mastication as well as the patient-reported symptoms.
RESULTS
At 6 months after radiotherapy, there was a large increase in the number of patients reporting problems with opening their mouth, fatigue, stiffness, and pain of the jaw. Sixty-eight percent of the patients had symptoms of TMD before oncological treatment and 94% and 81% had symptoms at the 6- and 12-month follow-up, respectively.
CONCLUSION
The signs and symptoms of TMD escalate after radiotherapy, with symptoms peaking at 6 months after radiotherapy. Most commonly, patients suffer from restricted mouth opening, stiffness, fatigue, and pain of the jaw.
背景
本研究旨在探讨头颈部癌症（HNC）患者在接受肿瘤治疗前后常见的颞下颌关节紊乱（TMD）症状。
方法
本研究纳入了 89 例接受放疗的 HNC 患者。患者在放疗前和放疗后 6 个月和 12 个月接受检查，以评估颞下颌颌和咀嚼肌的功能和压痛以及患者报告的症状。
结果
放疗后 6 个月，张口困难、疲劳、僵硬和颌痛的患者数量明显增加。68%的患者在肿瘤治疗前有 TMD 症状，94%和 81%的患者在 6 个月和 12 个月随访时有症状。
结论
放疗后 TMD 的体征和症状加重，症状在放疗后 6 个月达到高峰。最常见的是患者出现张口受限、僵硬、疲劳和颌痛。
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