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自身免疫性低血糖在糖皮质激素治疗后复发,硫唑嘌呤有效治疗

Autoimmune Hypoglycemia Relapse on Glucocorticoids, Effectively Treated with Azathioprine.

作者信息

Panikar Vijay, Joshi Shashank, Vadgama Jimit, Kamat Tejas, Wagle Tejal, Nasilkar Nikhil, Shah Niti, Sheikh Saalim, Jain Chandani

机构信息

Consultant, Department of Endocrinology, Lilavati Hospital and Research Centre, Mumbai, Maharashtra.

CPS Trainee, Department of Endocrinology, Lilavati Hospital and Research Centre, Mumbai, Maharashtra.

出版信息

J Assoc Physicians India. 2018 Dec;66(12):78-79.

PMID:31313558
Abstract

Autoimmune Hypoglycemia, though very rare in India, but can be challenging to manage. Insulin autoimmune syndrome (IAS) should be considered in any patient with hypoglycemia in the setting of unsuppressed insulin levels associated with anti-insulin or anti insulin receptor antibodies. We are reporting the clinical course of one such case of insulin autoimmune syndrome, who was initially treated with glucocorticoids. The patient relapsed and was later on treated effectively with Azathioprine for glucocorticoids failure and toxicity.

摘要

自身免疫性低血糖症在印度虽然非常罕见,但治疗起来可能具有挑战性。对于任何低血糖且胰岛素水平未受抑制并伴有抗胰岛素或抗胰岛素受体抗体的患者,都应考虑胰岛素自身免疫综合征(IAS)。我们报告了一例胰岛素自身免疫综合征患者的临床病程,该患者最初接受糖皮质激素治疗。患者复发,后来因糖皮质激素治疗失败和出现毒性反应而改用硫唑嘌呤进行有效治疗。

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