SimulTOF Systems, Virgin Instruments Corp, Marlborough, Massachusetts, 01752.
School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, 53705.
J Mass Spectrom. 2020 Aug;55(8):e4423. doi: 10.1002/jms.4423. Epub 2019 Aug 9.
A new high performance linear MALDI-TOF mass spectrometer provides both high spatial resolution and high speed. This instrument employs a new ion optics system with a grounded ion source and efficient transfer and detection of ions over a broad mass range. This provides very high sensitivity, precision, and an extended dynamic range for both positive and negative ion detection. Here we demonstrate the capabilities of this system by imaging pancreatic tissue samples from rats and mice.
一种新型高性能线性 MALDI-TOF 质谱仪兼具高空间分辨率和高速。该仪器采用了新型离子光学系统，带有接地离子源，并能在很宽的质量范围内高效传输和检测离子。这为正离子和负离子检测提供了极高的灵敏度、精度和扩展的动态范围。在这里，我们通过对来自大鼠和小鼠的胰腺组织样本成像来展示该系统的功能。
