炎症小体：不仅仅是一种保护性的先天免疫机制。
The Inflammasome: More Than a Protective Innate Immune Mechanism.
机构信息
MRC MHU, BRC Haematology Theme, Oxford Biomedical Research Centre, Oxford Centre for Haematology, WIMM, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
MRC MHU, BRC Haematology Theme, Oxford Biomedical Research Centre, Oxford Centre for Haematology, WIMM, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; Department of Haematology, Oxford University Hospitals NHS Trust, Oxford, UK.
出版信息
Immunity. 2019 Jul 16;51(1):3-5. doi: 10.1016/j.immuni.2019.06.022.
Little is known about the inflammasome beyond its function in innate immune response. In this issue of Immunity, Tyrkalska et al. report that the inflammasome regulates the balance between erythroid and myeloid differentiation in model systems, providing insights into hematopoietic lineage bias associated with inflammatory conditions.
除了在先天免疫反应中的作用外，人们对炎症小体知之甚少。在本期《免疫》杂志上，Tyrkalska 等人报道炎症小体在模型系统中调节红系和髓系分化之间的平衡，为炎症相关造血谱系偏倚提供了新的见解。
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